Appella E - Search Results

1

Tumor susceptibility and apoptosis defect in a mouse strain expressing a human p53 transgene.

Dudgeon C, Kek C, Demidov ON, Saito S, Fernandes K, Diot A, Bourdon JC, Lane DP, Appella E, Fornace AJ Jr, Bulavin DV. Dudgeon C, et al. Among authors: appella e. Cancer Res. 2006 Mar 15;66(6):2928-36. doi: 10.1158/0008-5472.CAN-05-2063. Cancer Res. 2006. PMID: 16540640

2

Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity.

Bulavin DV, Demidov ON, Saito S, Kauraniemi P, Phillips C, Amundson SA, Ambrosino C, Sauter G, Nebreda AR, Anderson CW, Kallioniemi A, Fornace AJ Jr, Appella E. Bulavin DV, et al. Among authors: appella e. Nat Genet. 2002 Jun;31(2):210-5. doi: 10.1038/ng894. Epub 2002 May 20. Nat Genet. 2002. PMID: 12021785

3

Regulation of ATM/p53-dependent suppression of myc-induced lymphomas by Wip1 phosphatase.

Shreeram S, Hee WK, Demidov ON, Kek C, Yamaguchi H, Fornace AJ Jr, Anderson CW, Appella E, Bulavin DV. Shreeram S, et al. Among authors: appella e. J Exp Med. 2006 Dec 25;203(13):2793-9. doi: 10.1084/jem.20061563. Epub 2006 Dec 11. J Exp Med. 2006. PMID: 17158963 Free PMC article.

4

Wip1 phosphatase regulates p53-dependent apoptosis of stem cells and tumorigenesis in the mouse intestine.

Demidov ON, Timofeev O, Lwin HN, Kek C, Appella E, Bulavin DV. Demidov ON, et al. Among authors: appella e. Cell Stem Cell. 2007 Aug 16;1(2):180-90. doi: 10.1016/j.stem.2007.05.020. Cell Stem Cell. 2007. PMID: 18371349 Free article.

5

Induction of PPM1D following DNA-damaging treatments through a conserved p53 response element coincides with a shift in the use of transcription initiation sites.

Rossi M, Demidov ON, Anderson CW, Appella E, Mazur SJ. Rossi M, et al. Among authors: appella e. Nucleic Acids Res. 2008 Dec;36(22):7168-80. doi: 10.1093/nar/gkn888. Epub 2008 Nov 10. Nucleic Acids Res. 2008. PMID: 19015127 Free PMC article.

6

Phosphorylation site interdependence of human p53 post-translational modifications in response to stress.

Saito S, Yamaguchi H, Higashimoto Y, Chao C, Xu Y, Fornace AJ Jr, Appella E, Anderson CW. Saito S, et al. Among authors: appella e. J Biol Chem. 2003 Sep 26;278(39):37536-44. doi: 10.1074/jbc.M305135200. Epub 2003 Jul 14. J Biol Chem. 2003. PMID: 12860987 Free article.

7

Inactivation of the Wip1 phosphatase inhibits mammary tumorigenesis through p38 MAPK-mediated activation of the p16(Ink4a)-p19(Arf) pathway.

Bulavin DV, Phillips C, Nannenga B, Timofeev O, Donehower LA, Anderson CW, Appella E, Fornace AJ Jr. Bulavin DV, et al. Among authors: appella e. Nat Genet. 2004 Apr;36(4):343-50. doi: 10.1038/ng1317. Epub 2004 Feb 29. Nat Genet. 2004. PMID: 14991053

8

ING2 regulates the onset of replicative senescence by induction of p300-dependent p53 acetylation.

Pedeux R, Sengupta S, Shen JC, Demidov ON, Saito S, Onogi H, Kumamoto K, Wincovitch S, Garfield SH, McMenamin M, Nagashima M, Grossman SR, Appella E, Harris CC. Pedeux R, et al. Among authors: appella e. Mol Cell Biol. 2005 Aug;25(15):6639-48. doi: 10.1128/MCB.25.15.6639-6648.2005. Mol Cell Biol. 2005. PMID: 16024799 Free PMC article.

9

Wip1 phosphatase-deficient mice exhibit defective T cell maturation due to sustained p53 activation.

Schito ML, Demidov ON, Saito S, Ashwell JD, Appella E. Schito ML, et al. Among authors: appella e. J Immunol. 2006 Apr 15;176(8):4818-25. doi: 10.4049/jimmunol.176.8.4818. J Immunol. 2006. PMID: 16585576

10

Wip1 phosphatase modulates ATM-dependent signaling pathways.

Shreeram S, Demidov ON, Hee WK, Yamaguchi H, Onishi N, Kek C, Timofeev ON, Dudgeon C, Fornace AJ, Anderson CW, Minami Y, Appella E, Bulavin DV. Shreeram S, et al. Among authors: appella e. Mol Cell. 2006 Sep 1;23(5):757-64. doi: 10.1016/j.molcel.2006.07.010. Mol Cell. 2006. PMID: 16949371 Free article.

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