Martínez A - Search Results

1

Adrenomedullin: a new and promising target for drug discovery.

García MA, Martín-Santamaría S, de Pascual-Teresa B, Ramos A, Julián M, Martínez A. García MA, et al. Among authors: martinez a. Expert Opin Ther Targets. 2006 Apr;10(2):303-17. doi: 10.1517/14728222.10.2.303. Expert Opin Ther Targets. 2006. PMID: 16548778 Review.

2

Adrenomedullin: a new target for the design of small molecule modulators with promising pharmacological activities.

Julián M, Cacho M, García MA, Martín-Santamaría S, de Pascual-Teresa B, Ramos A, Martínez A, Cuttitta F. Julián M, et al. Among authors: martinez a. Eur J Med Chem. 2005 Aug;40(8):737-50. doi: 10.1016/j.ejmech.2004.10.016. Eur J Med Chem. 2005. PMID: 15927308 Review.

3

Synthesis, biological evaluation, and three-dimensional quantitative structure-activity relationship study of small-molecule positive modulators of adrenomedullin.

García MA, Martín-Santamaría S, Cacho M, de la Llave FM, Julián M, Martínez A, de Pascual-Teresa B, Ramos A. García MA, et al. Among authors: martinez a. J Med Chem. 2005 Jun 16;48(12):4068-75. doi: 10.1021/jm050021+. J Med Chem. 2005. PMID: 15943480

4

Small-molecule negative modulators of adrenomedullin: design, synthesis, and 3D-QSAR study.

Roldós V, Martín-Santamaría S, Julián M, Martínez A, Choulier L, Altschuh D, de Pascual-Teresa B, Ramos A. Roldós V, et al. Among authors: martinez a. ChemMedChem. 2008 Sep;3(9):1345-55. doi: 10.1002/cmdc.200800066. ChemMedChem. 2008. PMID: 18759242

5

Potent "clicked" MMP2 inhibitors: synthesis, molecular modeling and biological exploration.

Zapico JM, Serra P, García-Sanmartín J, Filipiak K, Carbajo RJ, Schott AK, Pineda-Lucena A, Martínez A, Martín-Santamaría S, de Pascual-Teresa B, Ramos A. Zapico JM, et al. Among authors: martinez a. Org Biomol Chem. 2011 Jun 21;9(12):4587-99. doi: 10.1039/c0ob00852d. Epub 2011 May 6. Org Biomol Chem. 2011. PMID: 21552627

6

Structure of micelle-bound adrenomedullin: a first step toward the analysis of its interactions with receptors and small molecules.

Pérez-Castells J, Martín-Santamaría S, Nieto L, Ramos A, Martínez A, Pascual-Teresa Bd, Jiménez-Barbero J. Pérez-Castells J, et al. Among authors: martinez a. Biopolymers. 2012 Jan;97(1):45-53. doi: 10.1002/bip.21700. Epub 2011 Aug 9. Biopolymers. 2012. PMID: 21830197

7

Identification of first proadrenomedullin N-terminal 20 peptide (PAMP) modulator by means of virtual screening and NMR interaction experiments.

Roldós V, Carbajo RJ, Schott AK, Pineda-Lucena A, Ochoa-Callejero L, Martínez A, Ramos A, de Pascual-Teresa B. Roldós V, et al. Among authors: martinez a. Eur J Med Chem. 2012 Sep;55:262-72. doi: 10.1016/j.ejmech.2012.07.031. Epub 2012 Jul 27. Eur J Med Chem. 2012. PMID: 22884224

8

In silico identification and in vivo characterization of small molecule therapeutic hypothermia mimetics.

Coderch C, Díaz de Cerio M, Zapico JM, Peláez R, Larrayoz IM, Ramos A, Martínez A, de Pascual-Teresa B. Coderch C, et al. Among authors: martinez a. Bioorg Med Chem. 2017 Dec 15;25(24):6597-6604. doi: 10.1016/j.bmc.2017.10.039. Epub 2017 Oct 31. Bioorg Med Chem. 2017. PMID: 29137939

9

Adrenomedullin functions as an important tumor survival factor in human carcinogenesis.

Cuttitta F, Pío R, Garayoa M, Zudaire E, Julián M, Elsasser TH, Montuenga LM, Martínez A. Cuttitta F, et al. Among authors: martinez a. Microsc Res Tech. 2002 Apr 15;57(2):110-9. doi: 10.1002/jemt.10059. Microsc Res Tech. 2002. PMID: 11921362 Free article. Review.

10

Identification of vasoactive nonpeptidic positive and negative modulators of adrenomedullin using a neutralizing antibody-based screening strategy.

Martínez A, Julián M, Bregonzio C, Notari L, Moody TW, Cuttitta F. Martínez A, et al. Endocrinology. 2004 Aug;145(8):3858-65. doi: 10.1210/en.2003-1251. Epub 2004 Apr 23. Endocrinology. 2004. PMID: 15107357

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