Kastelein R - Search Results

1

Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression.

de Waal Malefyt R, Haanen J, Spits H, Roncarolo MG, te Velde A, Figdor C, Johnson K, Kastelein R, Yssel H, de Vries JE. de Waal Malefyt R, et al. Among authors: kastelein r. J Exp Med. 1991 Oct 1;174(4):915-24. doi: 10.1084/jem.174.4.915. J Exp Med. 1991. PMID: 1655948 Free PMC article.

2

T cell activation-inducing epitopes of the house dust mite allergen Der p I. Proliferation and lymphokine production patterns by Der p I-specific CD4+ T cell clones.

Yssel H, Johnson KE, Schneider PV, Wideman J, Terr A, Kastelein R, De Vries JE. Yssel H, et al. Among authors: kastelein r. J Immunol. 1992 Feb 1;148(3):738-45. J Immunol. 1992. PMID: 1370514

3

IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis.

Chan JR, Blumenschein W, Murphy E, Diveu C, Wiekowski M, Abbondanzo S, Lucian L, Geissler R, Brodie S, Kimball AB, Gorman DM, Smith K, de Waal Malefyt R, Kastelein RA, McClanahan TK, Bowman EP. Chan JR, et al. Among authors: kastelein ra. J Exp Med. 2006 Nov 27;203(12):2577-87. doi: 10.1084/jem.20060244. Epub 2006 Oct 30. J Exp Med. 2006. PMID: 17074928 Free PMC article.

4

Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling.

Boniface K, Bak-Jensen KS, Li Y, Blumenschein WM, McGeachy MJ, McClanahan TK, McKenzie BS, Kastelein RA, Cua DJ, de Waal Malefyt R. Boniface K, et al. Among authors: kastelein ra. J Exp Med. 2009 Mar 16;206(3):535-48. doi: 10.1084/jem.20082293. Epub 2009 Mar 9. J Exp Med. 2009. PMID: 19273625 Free PMC article.

5

Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI.

Vieira P, de Waal-Malefyt R, Dang MN, Johnson KE, Kastelein R, Fiorentino DF, deVries JE, Roncarolo MG, Mosmann TR, Moore KW. Vieira P, et al. Among authors: kastelein r. Proc Natl Acad Sci U S A. 1991 Feb 15;88(4):1172-6. doi: 10.1073/pnas.88.4.1172. Proc Natl Acad Sci U S A. 1991. PMID: 1847510 Free PMC article.

6

IL-4 inhibits IL-2-mediated induction of human lymphokine-activated killer cells, but not the generation of antigen-specific cytotoxic T lymphocytes in mixed leukocyte cultures.

Spits H, Yssel H, Paliard X, Kastelein R, Figdor C, de Vries JE. Spits H, et al. Among authors: kastelein r. J Immunol. 1988 Jul 1;141(1):29-36. J Immunol. 1988. PMID: 2454260

7

IL-27 and IFN-alpha signal via Stat1 and Stat3 and induce T-Bet and IL-12Rbeta2 in naive T cells.

Hibbert L, Pflanz S, De Waal Malefyt R, Kastelein RA. Hibbert L, et al. Among authors: kastelein ra. J Interferon Cytokine Res. 2003 Sep;23(9):513-22. doi: 10.1089/10799900360708632. J Interferon Cytokine Res. 2003. PMID: 14565860

8

WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27.

Pflanz S, Hibbert L, Mattson J, Rosales R, Vaisberg E, Bazan JF, Phillips JH, McClanahan TK, de Waal Malefyt R, Kastelein RA. Pflanz S, et al. Among authors: kastelein ra. J Immunol. 2004 Feb 15;172(4):2225-31. doi: 10.4049/jimmunol.172.4.2225. J Immunol. 2004. PMID: 14764690

9

Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation.

Kleinschek MA, Boniface K, Sadekova S, Grein J, Murphy EE, Turner SP, Raskin L, Desai B, Faubion WA, de Waal Malefyt R, Pierce RH, McClanahan T, Kastelein RA. Kleinschek MA, et al. Among authors: kastelein ra. J Exp Med. 2009 Mar 16;206(3):525-34. doi: 10.1084/jem.20081712. Epub 2009 Mar 9. J Exp Med. 2009. PMID: 19273624 Free PMC article.

10

IL-18 receptors, their role in ligand binding and function: anti-IL-1RAcPL antibody, a potent antagonist of IL-18.

Debets R, Timans JC, Churakowa T, Zurawski S, de Waal Malefyt R, Moore KW, Abrams JS, O'Garra A, Bazan JF, Kastelein RA. Debets R, et al. Among authors: kastelein ra. J Immunol. 2000 Nov 1;165(9):4950-6. doi: 10.4049/jimmunol.165.9.4950. J Immunol. 2000. PMID: 11046021

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