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The chromosome 6p22 haplotype associated with dyslexia reduces the expression of KIAA0319, a novel gene involved in neuronal migration.
Paracchini S, Thomas A, Castro S, Lai C, Paramasivam M, Wang Y, Keating BJ, Taylor JM, Hacking DF, Scerri T, Francks C, Richardson AJ, Wade-Martins R, Stein JF, Knight JC, Copp AJ, Loturco J, Monaco AP. Paracchini S, et al. Among authors: wang y. Hum Mol Genet. 2006 May 15;15(10):1659-66. doi: 10.1093/hmg/ddl089. Epub 2006 Apr 6. Hum Mol Genet. 2006. PMID: 16600991
DYX1C1 functions in neuronal migration in developing neocortex.
Wang Y, Paramasivam M, Thomas A, Bai J, Kaminen-Ahola N, Kere J, Voskuil J, Rosen GD, Galaburda AM, Loturco JJ. Wang Y, et al. Neuroscience. 2006 Dec 1;143(2):515-22. doi: 10.1016/j.neuroscience.2006.08.022. Epub 2006 Sep 20. Neuroscience. 2006. PMID: 16989952
DCDC2 is associated with reading disability and modulates neuronal development in the brain.
Meng H, Smith SD, Hager K, Held M, Liu J, Olson RK, Pennington BF, DeFries JC, Gelernter J, O'Reilly-Pol T, Somlo S, Skudlarski P, Shaywitz SE, Shaywitz BA, Marchione K, Wang Y, Paramasivam M, LoTurco JJ, Page GP, Gruen JR. Meng H, et al. Among authors: wang y. Proc Natl Acad Sci U S A. 2005 Nov 22;102(47):17053-8. doi: 10.1073/pnas.0508591102. Epub 2005 Nov 8. Proc Natl Acad Sci U S A. 2005. PMID: 16278297 Free PMC article.
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