Mentens N - Search Results

1

Efficacy of the kinase inhibitor SU11248 against gastrointestinal stromal tumor mutants refractory to imatinib mesylate.

Prenen H, Cools J, Mentens N, Folens C, Sciot R, Schöffski P, Van Oosterom A, Marynen P, Debiec-Rychter M. Prenen H, et al. Among authors: mentens n. Clin Cancer Res. 2006 Apr 15;12(8):2622-7. doi: 10.1158/1078-0432.CCR-05-2275. Clin Cancer Res. 2006. PMID: 16638875

2

Mechanisms of resistance to imatinib mesylate in gastrointestinal stromal tumors and activity of the PKC412 inhibitor against imatinib-resistant mutants.

Debiec-Rychter M, Cools J, Dumez H, Sciot R, Stul M, Mentens N, Vranckx H, Wasag B, Prenen H, Roesel J, Hagemeijer A, Van Oosterom A, Marynen P. Debiec-Rychter M, et al. Among authors: mentens n. Gastroenterology. 2005 Feb;128(2):270-9. doi: 10.1053/j.gastro.2004.11.020. Gastroenterology. 2005. PMID: 15685537

3

Sorafenib is a potent inhibitor of FIP1L1-PDGFRalpha and the imatinib-resistant FIP1L1-PDGFRalpha T674I mutant.

Lierman E, Folens C, Stover EH, Mentens N, Van Miegroet H, Scheers W, Boogaerts M, Vandenberghe P, Marynen P, Cools J. Lierman E, et al. Among authors: mentens n. Blood. 2006 Aug 15;108(4):1374-6. doi: 10.1182/blood-2006-02-004457. Epub 2006 Apr 27. Blood. 2006. PMID: 16645167 Free PMC article.

4

Intestinal neurofibromatosis is a subtype of familial GIST and results from a dominant activating mutation in PDGFRA.

de Raedt T, Cools J, Debiec-Rychter M, Brems H, Mentens N, Sciot R, Himpens J, de Wever I, Schöffski P, Marynen P, Legius E. de Raedt T, et al. Among authors: mentens n. Gastroenterology. 2006 Dec;131(6):1907-12. doi: 10.1053/j.gastro.2006.07.002. Gastroenterology. 2006. PMID: 17087943

5

Prediction of resistance to small molecule FLT3 inhibitors: implications for molecularly targeted therapy of acute leukemia.

Cools J, Mentens N, Furet P, Fabbro D, Clark JJ, Griffin JD, Marynen P, Gilliland DG. Cools J, et al. Among authors: mentens n. Cancer Res. 2004 Sep 15;64(18):6385-9. doi: 10.1158/0008-5472.CAN-04-2148. Cancer Res. 2004. PMID: 15374944

6

Fusion of EML1 to ABL1 in T-cell acute lymphoblastic leukemia with cryptic t(9;14)(q34;q32).

De Keersmaecker K, Graux C, Odero MD, Mentens N, Somers R, Maertens J, Wlodarska I, Vandenberghe P, Hagemeijer A, Marynen P, Cools J. De Keersmaecker K, et al. Among authors: mentens n. Blood. 2005 Jun 15;105(12):4849-52. doi: 10.1182/blood-2004-12-4897. Epub 2005 Feb 15. Blood. 2005. PMID: 15713800 Free article.

7

The ability of sorafenib to inhibit oncogenic PDGFRbeta and FLT3 mutants and overcome resistance to other small molecule inhibitors.

Lierman E, Lahortiga I, Van Miegroet H, Mentens N, Marynen P, Cools J. Lierman E, et al. Among authors: mentens n. Haematologica. 2007 Jan;92(1):27-34. doi: 10.3324/haematol.10692. Haematologica. 2007. PMID: 17229632 Free article.

8

Activity of imatinib in systemic mastocytosis with chronic basophilic leukemia and a PRKG2-PDGFRB fusion.

Lahortiga I, Akin C, Cools J, Wilson TM, Mentens N, Arthur DC, Maric I, Noel P, Kocabas C, Marynen P, Lessin LS, Wlodarska I, Robyn J, Metcalfe DD. Lahortiga I, et al. Among authors: mentens n. Haematologica. 2008 Jan;93(1):49-56. doi: 10.3324/haematol.11836. Haematologica. 2008. PMID: 18166785 Free article.

9

In vitro validation of gamma-secretase inhibitors alone or in combination with other anti-cancer drugs for the treatment of T-cell acute lymphoblastic leukemia.

De Keersmaecker K, Lahortiga I, Mentens N, Folens C, Van Neste L, Bekaert S, Vandenberghe P, Odero MD, Marynen P, Cools J. De Keersmaecker K, et al. Among authors: mentens n. Haematologica. 2008 Apr;93(4):533-42. doi: 10.3324/haematol.11894. Epub 2008 Mar 5. Haematologica. 2008. PMID: 18322257 Free article.

10

The XPO1 Inhibitor KPT-8602 Synergizes with Dexamethasone in Acute Lymphoblastic Leukemia.

Verbeke D, Demeyer S, Prieto C, de Bock CE, De Bie J, Gielen O, Jacobs K, Mentens N, Verhoeven BM, Uyttebroeck A, Boeckx N, De Keersmaecker K, Maertens J, Segers H, Cools J. Verbeke D, et al. Among authors: mentens n. Clin Cancer Res. 2020 Nov 1;26(21):5747-5758. doi: 10.1158/1078-0432.CCR-20-1315. Epub 2020 Aug 21. Clin Cancer Res. 2020. PMID: 32826328

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