Kramer L - Search Results

1

The three-substituted indolinone cyclin-dependent kinase 2 inhibitor 3-[1-(3H-imidazol-4-yl)-meth-(Z)-ylidene]-5-methoxy-1,3-dihydro-indol-2-one (SU9516) kills human leukemia cells via down-regulation of Mcl-1 through a transcriptional mechanism.

Gao N, Kramer L, Rahmani M, Dent P, Grant S. Gao N, et al. Among authors: kramer l. Mol Pharmacol. 2006 Aug;70(2):645-55. doi: 10.1124/mol.106.024505. Epub 2006 May 3. Mol Pharmacol. 2006. PMID: 16672643

2

The histone deacetylase inhibitor MS-275 interacts synergistically with fludarabine to induce apoptosis in human leukemia cells.

Maggio SC, Rosato RR, Kramer LB, Dai Y, Rahmani M, Paik DS, Czarnik AC, Payne SG, Spiegel S, Grant S. Maggio SC, et al. Cancer Res. 2004 Apr 1;64(7):2590-600. doi: 10.1158/0008-5472.can-03-2631. Cancer Res. 2004. PMID: 15059916

3

Cotreatment with suberanoylanilide hydroxamic acid and 17-allylamino 17-demethoxygeldanamycin synergistically induces apoptosis in Bcr-Abl+ Cells sensitive and resistant to STI571 (imatinib mesylate) in association with down-regulation of Bcr-Abl, abrogation of signal transducer and activator of transcription 5 activity, and Bax conformational change.

Rahmani M, Reese E, Dai Y, Bauer C, Kramer LB, Huang M, Jove R, Dent P, Grant S. Rahmani M, et al. Mol Pharmacol. 2005 Apr;67(4):1166-76. doi: 10.1124/mol.104.007831. Epub 2004 Dec 29. Mol Pharmacol. 2005. PMID: 15625278

4

Interactions between 2-fluoroadenine 9-beta-D-arabinofuranoside and the kinase inhibitor UCN-01 in human leukemia and lymphoma cells.

Harvey S, Decker R, Dai Y, Schaefer G, Tang L, Kramer L, Dent P, Grant S. Harvey S, et al. Among authors: kramer l. Clin Cancer Res. 2001 Feb;7(2):320-30. Clin Cancer Res. 2001. PMID: 11234887

5

Agents that down-regulate or inhibit protein kinase C circumvent resistance to 1-beta-D-arabinofuranosylcytosine-induced apoptosis in human leukemia cells that overexpress Bcl-2.

Wang S, Vrana JA, Bartimole TM, Freemerman AJ, Jarvis WD, Kramer LB, Krystal G, Dent P, Grant S. Wang S, et al. Among authors: kramer lb. Mol Pharmacol. 1997 Dec;52(6):1000-9. doi: 10.1124/mol.52.6.1000. Mol Pharmacol. 1997. PMID: 9396780

6

Inhibition of protein kinase C activator-mediated induction of p21CIP1 and p27KIP1 by deoxycytidine analogs in human leukemia cells: relationship to apoptosis and differentiation.

Vrana JA, Kramer LB, Saunders AM, Zhang XF, Dent P, Povirk LF, Grant S. Vrana JA, et al. Among authors: kramer lb. Biochem Pharmacol. 1999 Jul 1;58(1):121-31. doi: 10.1016/s0006-2952(99)00077-5. Biochem Pharmacol. 1999. PMID: 10403525

7

Enforced expression of the tumor suppressor p53 renders human leukemia cells (U937) more sensitive to 1-[beta-D-arabinofuranosyl]cytosine (ara-C)-induced apoptosis.

Decker RH, Levin J, Kramer LB, Dai Y, Grant S. Decker RH, et al. Biochem Pharmacol. 2003 Jun 15;65(12):1997-2008. doi: 10.1016/s0006-2952(03)00149-7. Biochem Pharmacol. 2003. PMID: 12787880

8

Interactions between bortezomib and romidepsin and belinostat in chronic lymphocytic leukemia cells.

Dai Y, Chen S, Kramer LB, Funk VL, Dent P, Grant S. Dai Y, et al. Among authors: kramer lb. Clin Cancer Res. 2008 Jan 15;14(2):549-58. doi: 10.1158/1078-0432.CCR-07-1934. Clin Cancer Res. 2008. PMID: 18223231

9

Interruption of the Ras/MEK/ERK signaling cascade enhances Chk1 inhibitor-induced DNA damage in vitro and in vivo in human multiple myeloma cells.

Dai Y, Chen S, Pei XY, Almenara JA, Kramer LB, Venditti CA, Dent P, Grant S. Dai Y, et al. Blood. 2008 Sep 15;112(6):2439-49. doi: 10.1182/blood-2008-05-159392. Epub 2008 Jul 9. Blood. 2008. PMID: 18614762 Free PMC article.

10

Disruption of Src function potentiates Chk1-inhibitor-induced apoptosis in human multiple myeloma cells in vitro and in vivo.

Dai Y, Chen S, Shah R, Pei XY, Wang L, Almenara JA, Kramer LB, Dent P, Grant S. Dai Y, et al. Among authors: kramer lb. Blood. 2011 Feb 10;117(6):1947-57. doi: 10.1182/blood-2010-06-291146. Epub 2010 Dec 10. Blood. 2011. PMID: 21148814 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

1,293 results

Search Page

Filters