Moudgil R - Search Results

1

A central role for oxygen-sensitive K+ channels and mitochondria in the specialized oxygen-sensing system.

Archer SL, Michelakis ED, Thébaud B, Bonnet S, Moudgil R, Wu XC, Weir EK. Archer SL, et al. Among authors: moudgil r. Novartis Found Symp. 2006;272:157-71; discussion 171-5, 214-7. Novartis Found Symp. 2006. PMID: 16686435 Review.

2

Gene transfer and metabolic modulators as new therapies for pulmonary hypertension. Increasing expression and activity of potassium channels in rat and human models.

Michelakis ED, Dyck JR, McMurtry MS, Wang S, Wu XC, Moudgil R, Hashimoto K, Puttagunta L, Archer SL. Michelakis ED, et al. Among authors: moudgil r. Adv Exp Med Biol. 2001;502:401-18. doi: 10.1007/978-1-4757-3401-0_26. Adv Exp Med Biol. 2001. PMID: 11950153

3

Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats: role of increased expression and activity of voltage-gated potassium channels.

Michelakis ED, McMurtry MS, Wu XC, Dyck JR, Moudgil R, Hopkins TA, Lopaschuk GD, Puttagunta L, Waite R, Archer SL. Michelakis ED, et al. Among authors: moudgil r. Circulation. 2002 Jan 15;105(2):244-50. doi: 10.1161/hc0202.101974. Circulation. 2002. PMID: 11790708

4

In vivo gene transfer of the O2-sensitive potassium channel Kv1.5 reduces pulmonary hypertension and restores hypoxic pulmonary vasoconstriction in chronically hypoxic rats.

Pozeg ZI, Michelakis ED, McMurtry MS, Thébaud B, Wu XC, Dyck JR, Hashimoto K, Wang S, Moudgil R, Harry G, Sultanian R, Koshal A, Archer SL. Pozeg ZI, et al. Among authors: moudgil r. Circulation. 2003 Apr 22;107(15):2037-44. doi: 10.1161/01.CIR.0000062688.76508.B3. Epub 2003 Apr 14. Circulation. 2003. PMID: 12695303

5

O2 sensing in the human ductus arteriosus: redox-sensitive K+ channels are regulated by mitochondria-derived hydrogen peroxide.

Archer SL, Wu XC, Thébaud B, Moudgil R, Hashimoto K, Michelakis ED. Archer SL, et al. Among authors: moudgil r. Biol Chem. 2004 Mar-Apr;385(3-4):205-16. doi: 10.1515/BC.2004.014. Biol Chem. 2004. PMID: 15134333 Review.

6

The neurovascular mechanism of clitoral erection: nitric oxide and cGMP-stimulated activation of BKCa channels.

Gragasin FS, Michelakis ED, Hogan A, Moudgil R, Hashimoto K, Wu X, Bonnet S, Haromy A, Archer SL. Gragasin FS, et al. Among authors: moudgil r. FASEB J. 2004 Sep;18(12):1382-91. doi: 10.1096/fj.04-1978com. FASEB J. 2004. PMID: 15333581

7

Oxygen-sensitive Kv channel gene transfer confers oxygen responsiveness to preterm rabbit and remodeled human ductus arteriosus: implications for infants with patent ductus arteriosus.

Thébaud B, Michelakis ED, Wu XC, Moudgil R, Kuzyk M, Dyck JR, Harry G, Hashimoto K, Haromy A, Rebeyka I, Archer SL. Thébaud B, et al. Among authors: moudgil r. Circulation. 2004 Sep 14;110(11):1372-9. doi: 10.1161/01.CIR.0000141292.28616.65. Epub 2004 Sep 7. Circulation. 2004. PMID: 15353504

8

An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension.

Bonnet S, Michelakis ED, Porter CJ, Andrade-Navarro MA, Thébaud B, Bonnet S, Haromy A, Harry G, Moudgil R, McMurtry MS, Weir EK, Archer SL. Bonnet S, et al. Among authors: moudgil r. Circulation. 2006 Jun 6;113(22):2630-41. doi: 10.1161/CIRCULATIONAHA.105.609008. Epub 2006 May 30. Circulation. 2006. PMID: 16735674

9

The role of k+ channels in determining pulmonary vascular tone, oxygen sensing, cell proliferation, and apoptosis: implications in hypoxic pulmonary vasoconstriction and pulmonary arterial hypertension.

Moudgil R, Michelakis ED, Archer SL. Moudgil R, et al. Microcirculation. 2006 Dec;13(8):615-32. doi: 10.1080/10739680600930222. Microcirculation. 2006. PMID: 17085423 Review.

10

Oxygen activates the Rho/Rho-kinase pathway and induces RhoB and ROCK-1 expression in human and rabbit ductus arteriosus by increasing mitochondria-derived reactive oxygen species: a newly recognized mechanism for sustaining ductal constriction.

Kajimoto H, Hashimoto K, Bonnet SN, Haromy A, Harry G, Moudgil R, Nakanishi T, Rebeyka I, Thébaud B, Michelakis ED, Archer SL. Kajimoto H, et al. Among authors: moudgil r. Circulation. 2007 Apr 3;115(13):1777-88. doi: 10.1161/CIRCULATIONAHA.106.649566. Epub 2007 Mar 12. Circulation. 2007. PMID: 17353442

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