Agents which reverse multidrug-resistance are inhibitors of [3H]vinblastine transport by isolated vesicles.
Horio M, Lovelace E, Pastan I, Gottesman MM.
Horio M, et al. Among authors: pastan i.
Biochim Biophys Acta. 1991 Jan 9;1061(1):106-10. doi: 10.1016/0005-2736(91)90274-c.
Biochim Biophys Acta. 1991.
PMID: 1671642
We have previously reported that plasma membrane vesicles partially purified from multidrug-resistant human KB carcinoma cells, but not from drug-sensitive cells, accumulated [3H]vinblastine in an ATP-dependent manner (Horio, M., Gottesman, M.M. and Pastan, I. (1988 …
We have previously reported that plasma membrane vesicles partially purified from multidrug-resistant human KB carcinoma cells, but not from …