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Pyrrolo[1,3]benzothiazepine-based atypical antipsychotic agents. Synthesis, structure-activity relationship, molecular modeling, and biological studies.
Campiani G, Butini S, Gemma S, Nacci V, Fattorusso C, Catalanotti B, Giorgi G, Cagnotto A, Goegan M, Mennini T, Minetti P, Di Cesare MA, Mastroianni D, Scafetta N, Galletti B, Stasi MA, Castorina M, Pacifici L, Ghirardi O, Tinti O, Carminati P. Campiani G, et al. Among authors: mastroianni d. J Med Chem. 2002 Jan 17;45(2):344-59. doi: 10.1021/jm010982y. J Med Chem. 2002. PMID: 11784139
Pyrrolo[1,3]benzothiazepine-based serotonin and dopamine receptor antagonists. Molecular modeling, further structure-activity relationship studies, and identification of novel atypical antipsychotic agents.
Campiani G, Butini S, Fattorusso C, Catalanotti B, Gemma S, Nacci V, Morelli E, Cagnotto A, Mereghetti I, Mennini T, Carli M, Minetti P, Di Cesare MA, Mastroianni D, Scafetta N, Galletti B, Stasi MA, Castorina M, Pacifici L, Vertechy M, Di Serio S, Ghirardi O, Tinti O, Carminati P. Campiani G, et al. Among authors: mastroianni d. J Med Chem. 2004 Jan 1;47(1):143-57. doi: 10.1021/jm0309811. J Med Chem. 2004. PMID: 14695828
Synthesis, biological evaluation and metadynamics simulations of novel N-methyl β-sheet breaker peptides as inhibitors of Alzheimer's β-amyloid fibrillogenesis.
Moraca F, Vespoli I, Mastroianni D, Piscopo V, Gaglione R, Arciello A, De Nisco M, Pacifico S, Catalanotti B, Pedatella S. Moraca F, et al. Among authors: mastroianni d. RSC Med Chem. 2024 Apr 11;15(7):2286-2299. doi: 10.1039/d4md00057a. eCollection 2024 Jul 17. RSC Med Chem. 2024. PMID: 39026638
15 results