A combination therapy with simvastatin and ursodeoxycholic acid is more effective for cholesterol gallstone dissolution than is ursodeoxycholic acid monotherapy.
Tazuma S, Kajiyama G, Mizuno T, Yamashita G, Miura H, Kajihara T, Hattori Y, Miyake H, Nishioka T, Hyogo H, Sunami Y, Yasumiba S, Ochi H, Matsumoto T, Abe A, Adachi K, Omata F, Ueno F, Sugata F, Ohguri S, Shibata H, Kokubu S.
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J Clin Gastroenterol. 1998 Jun;26(4):287-91. doi: 10.1097/00004836-199806000-00015.
J Clin Gastroenterol. 1998.
PMID: 9649013
Clinical Trial.