Crews CM - Search Results

1

Targeted gene disruption of methionine aminopeptidase 2 results in an embryonic gastrulation defect and endothelial cell growth arrest.

Yeh JJ, Ju R, Brdlik CM, Zhang W, Zhang Y, Matyskiela ME, Shotwell JD, Crews CM. Yeh JJ, et al. Among authors: crews cm. Proc Natl Acad Sci U S A. 2006 Jul 5;103(27):10379-10384. doi: 10.1073/pnas.0511313103. Epub 2006 Jun 21. Proc Natl Acad Sci U S A. 2006. PMID: 16790550 Free PMC article.

2

The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2.

Sin N, Meng L, Wang MQ, Wen JJ, Bornmann WG, Crews CM. Sin N, et al. Among authors: crews cm. Proc Natl Acad Sci U S A. 1997 Jun 10;94(12):6099-103. doi: 10.1073/pnas.94.12.6099. Proc Natl Acad Sci U S A. 1997. PMID: 9177176 Free PMC article.

3

Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity.

Meng L, Mohan R, Kwok BH, Elofsson M, Sin N, Crews CM. Meng L, et al. Among authors: crews cm. Proc Natl Acad Sci U S A. 1999 Aug 31;96(18):10403-8. doi: 10.1073/pnas.96.18.10403. Proc Natl Acad Sci U S A. 1999. PMID: 10468620 Free PMC article.

4

The antiangiogenic agent TNP-470 requires p53 and p21CIP/WAF for endothelial cell growth arrest.

Yeh JR, Mohan R, Crews CM. Yeh JR, et al. Among authors: crews cm. Proc Natl Acad Sci U S A. 2000 Nov 7;97(23):12782-7. doi: 10.1073/pnas.97.23.12782. Proc Natl Acad Sci U S A. 2000. PMID: 11070090 Free PMC article.

5

A single amino acid residue defines the difference in ovalicin sensitivity between type I and II methionine aminopeptidases.

Brdlik CM, Crews CM. Brdlik CM, et al. Among authors: crews cm. J Biol Chem. 2004 Mar 5;279(10):9475-80. doi: 10.1074/jbc.M307246200. Epub 2003 Dec 15. J Biol Chem. 2004. PMID: 14676204 Free PMC article.

6

A chemical and genetic approach to the mode of action of fumagillin.

Zhang Y, Yeh JR, Mara A, Ju R, Hines JF, Cirone P, Griesbach HL, Schneider I, Slusarski DC, Holley SA, Crews CM. Zhang Y, et al. Among authors: crews cm. Chem Biol. 2006 Sep;13(9):1001-9. doi: 10.1016/j.chembiol.2006.07.010. Chem Biol. 2006. PMID: 16984890 Free PMC article.

7

Triptolide is a traditional Chinese medicine-derived inhibitor of polycystic kidney disease.

Leuenroth SJ, Okuhara D, Shotwell JD, Markowitz GS, Yu Z, Somlo S, Crews CM. Leuenroth SJ, et al. Among authors: crews cm. Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4389-94. doi: 10.1073/pnas.0700499104. Epub 2007 Mar 6. Proc Natl Acad Sci U S A. 2007. PMID: 17360534 Free PMC article.

8

A role for planar cell polarity signaling in angiogenesis.

Cirone P, Lin S, Griesbach HL, Zhang Y, Slusarski DC, Crews CM. Cirone P, et al. Among authors: crews cm. Angiogenesis. 2008;11(4):347-60. doi: 10.1007/s10456-008-9116-2. Epub 2008 Sep 17. Angiogenesis. 2008. PMID: 18798004 Free PMC article.

9

Activation of the planar cell polarity formin DAAM1 leads to inhibition of endothelial cell proliferation, migration, and angiogenesis.

Ju R, Cirone P, Lin S, Griesbach H, Slusarski DC, Crews CM. Ju R, et al. Among authors: crews cm. Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):6906-11. doi: 10.1073/pnas.1001075107. Epub 2010 Mar 29. Proc Natl Acad Sci U S A. 2010. PMID: 20351293 Free PMC article.

10

Reversal of TNP-470-induced endothelial cell growth arrest by guanine and guanine nucleosides.

Hines J, Ju R, Dutschman GE, Cheng YC, Crews CM. Hines J, et al. Among authors: crews cm. J Pharmacol Exp Ther. 2010 Sep 1;334(3):729-38. doi: 10.1124/jpet.110.169110. Epub 2010 Jun 22. J Pharmacol Exp Ther. 2010. PMID: 20571059 Free PMC article.

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