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Induction of Noxa-mediated apoptosis by modified vaccinia virus Ankara depends on viral recognition by cytosolic helicases, leading to IRF-3/IFN-β-dependent induction of pro-apoptotic Noxa.
Eitz Ferrer P, Potthoff S, Kirschnek S, Gasteiger G, Kastenmüller W, Ludwig H, Paschen SA, Villunger A, Sutter G, Drexler I, Häcker G. Eitz Ferrer P, et al. Among authors: hacker g. PLoS Pathog. 2011 Jun;7(6):e1002083. doi: 10.1371/journal.ppat.1002083. Epub 2011 Jun 16. PLoS Pathog. 2011. PMID: 21698224 Free PMC article.
The NOXA-MCL1-BIM axis defines lifespan on extended mitotic arrest.
Haschka MD, Soratroi C, Kirschnek S, Häcker G, Hilbe R, Geley S, Villunger A, Fava LL. Haschka MD, et al. Among authors: hacker g. Nat Commun. 2015 Apr 29;6:6891. doi: 10.1038/ncomms7891. Nat Commun. 2015. PMID: 25922916 Free PMC article.
296 results