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Page 1
Identification of a novel member of the carboxylesterase family that hydrolyzes triacylglycerol: a potential role in adipocyte lipolysis.
Okazaki H, Igarashi M, Nishi M, Tajima M, Sekiya M, Okazaki S, Yahagi N, Ohashi K, Tsukamoto K, Amemiya-Kudo M, Matsuzaka T, Shimano H, Yamada N, Aoki J, Morikawa R, Takanezawa Y, Arai H, Nagai R, Kadowaki T, Osuga J, Ishibashi S. Okazaki H, et al. Among authors: nagai r. Diabetes. 2006 Jul;55(7):2091-7. doi: 10.2337/db05-0585. Diabetes. 2006. PMID: 16804080
Absence of hormone-sensitive lipase inhibits obesity and adipogenesis in Lep ob/ob mice.
Sekiya M, Osuga J, Okazaki H, Yahagi N, Harada K, Shen WJ, Tamura Y, Tomita S, Iizuka Y, Ohashi K, Okazaki M, Sata M, Nagai R, Fujita T, Shimano H, Kraemer FB, Yamada N, Ishibashi S. Sekiya M, et al. Among authors: nagai r. J Biol Chem. 2004 Apr 9;279(15):15084-90. doi: 10.1074/jbc.M310985200. Epub 2004 Jan 28. J Biol Chem. 2004. PMID: 14752112 Free article.
SREBP-1-independent regulation of lipogenic gene expression in adipocytes.
Sekiya M, Yahagi N, Matsuzaka T, Takeuchi Y, Nakagawa Y, Takahashi H, Okazaki H, Iizuka Y, Ohashi K, Gotoda T, Ishibashi S, Nagai R, Yamazaki T, Kadowaki T, Yamada N, Osuga J, Shimano H. Sekiya M, et al. Among authors: nagai r. J Lipid Res. 2007 Jul;48(7):1581-91. doi: 10.1194/jlr.M700033-JLR200. Epub 2007 Apr 24. J Lipid Res. 2007. PMID: 17456898 Free article.
Hormone-sensitive lipase is involved in hepatic cholesteryl ester hydrolysis.
Sekiya M, Osuga J, Yahagi N, Okazaki H, Tamura Y, Igarashi M, Takase S, Harada K, Okazaki S, Iizuka Y, Ohashi K, Yagyu H, Okazaki M, Gotoda T, Nagai R, Kadowaki T, Shimano H, Yamada N, Ishibashi S. Sekiya M, et al. Among authors: nagai r. J Lipid Res. 2008 Aug;49(8):1829-38. doi: 10.1194/jlr.M800198-JLR200. Epub 2008 May 14. J Lipid Res. 2008. PMID: 18480494 Free article.
Identification of neutral cholesterol ester hydrolase, a key enzyme removing cholesterol from macrophages.
Okazaki H, Igarashi M, Nishi M, Sekiya M, Tajima M, Takase S, Takanashi M, Ohta K, Tamura Y, Okazaki S, Yahagi N, Ohashi K, Amemiya-Kudo M, Nakagawa Y, Nagai R, Kadowaki T, Osuga J, Ishibashi S. Okazaki H, et al. Among authors: nagai r. J Biol Chem. 2008 Nov 28;283(48):33357-64. doi: 10.1074/jbc.M802686200. Epub 2008 Sep 9. J Biol Chem. 2008. PMID: 18782767 Free PMC article.
Polyunsaturated fatty acids selectively suppress sterol regulatory element-binding protein-1 through proteolytic processing and autoloop regulatory circuit.
Takeuchi Y, Yahagi N, Izumida Y, Nishi M, Kubota M, Teraoka Y, Yamamoto T, Matsuzaka T, Nakagawa Y, Sekiya M, Iizuka Y, Ohashi K, Osuga J, Gotoda T, Ishibashi S, Itaka K, Kataoka K, Nagai R, Yamada N, Kadowaki T, Shimano H. Takeuchi Y, et al. Among authors: nagai r. J Biol Chem. 2010 Apr 9;285(15):11681-91. doi: 10.1074/jbc.M109.096107. Epub 2010 Feb 9. J Biol Chem. 2010. PMID: 20145241 Free PMC article.
Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates fatty livers but not obesity or insulin resistance in Lep(ob)/Lep(ob) mice.
Yahagi N, Shimano H, Hasty AH, Matsuzaka T, Ide T, Yoshikawa T, Amemiya-Kudo M, Tomita S, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Osuga J, Harada K, Gotoda T, Nagai R, Ishibashi S, Yamada N. Yahagi N, et al. Among authors: nagai r. J Biol Chem. 2002 May 31;277(22):19353-7. doi: 10.1074/jbc.M201584200. Epub 2002 Mar 28. J Biol Chem. 2002. PMID: 11923308 Free article.
p53 Activation in adipocytes of obese mice.
Yahagi N, Shimano H, Matsuzaka T, Najima Y, Sekiya M, Nakagawa Y, Ide T, Tomita S, Okazaki H, Tamura Y, Iizuka Y, Ohashi K, Gotoda T, Nagai R, Kimura S, Ishibashi S, Osuga J, Yamada N. Yahagi N, et al. Among authors: nagai r. J Biol Chem. 2003 Jul 11;278(28):25395-400. doi: 10.1074/jbc.M302364200. Epub 2003 May 6. J Biol Chem. 2003. PMID: 12734185 Free article.
1,795 results