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The dominant role of CD8+ dendritic cells in cross-presentation is not dictated by antigen capture.
Schnorrer P, Behrens GM, Wilson NS, Pooley JL, Smith CM, El-Sukkari D, Davey G, Kupresanin F, Li M, Maraskovsky E, Belz GT, Carbone FR, Shortman K, Heath WR, Villadangos JA. Schnorrer P, et al. Among authors: pooley jl. Proc Natl Acad Sci U S A. 2006 Jul 11;103(28):10729-34. doi: 10.1073/pnas.0601956103. Epub 2006 Jun 28. Proc Natl Acad Sci U S A. 2006. PMID: 16807294 Free PMC article.
Disruption of the langerin/CD207 gene abolishes Birbeck granules without a marked loss of Langerhans cell function.
Kissenpfennig A, Aït-Yahia S, Clair-Moninot V, Stössel H, Badell E, Bordat Y, Pooley JL, Lang T, Prina E, Coste I, Gresser O, Renno T, Winter N, Milon G, Shortman K, Romani N, Lebecque S, Malissen B, Saeland S, Douillard P. Kissenpfennig A, et al. Among authors: pooley jl. Mol Cell Biol. 2005 Jan;25(1):88-99. doi: 10.1128/MCB.25.1.88-99.2005. Mol Cell Biol. 2005. PMID: 15601833 Free PMC article.