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Mitogen-activated protein kinase phosphatase-1 (MKP-1) expression is induced by low oxygen conditions found in solid tumor microenvironments. A candidate MKP for the inactivation of hypoxia-inducible stress-activated protein kinase/c-Jun N-terminal protein kinase activity.
Laderoute KR, Mendonca HL, Calaoagan JM, Knapp AM, Giaccia AJ, Stork PJ. Laderoute KR, et al. J Biol Chem. 1999 Apr 30;274(18):12890-7. doi: 10.1074/jbc.274.18.12890. J Biol Chem. 1999. PMID: 10212278 Free article.
A novel steroidal inhibitor of estrogen-related receptor alpha (ERR alpha).
Duellman SJ, Calaoagan JM, Sato BG, Fine R, Klebansky B, Chao WR, Hobbs P, Collins N, Sambucetti L, Laderoute KR. Duellman SJ, et al. Among authors: laderoute kr. Biochem Pharmacol. 2010 Sep 15;80(6):819-26. doi: 10.1016/j.bcp.2010.05.024. Epub 2010 May 31. Biochem Pharmacol. 2010. PMID: 20513360 Free PMC article.
57 results