Heemskerk JW - Search Results

1

Continuous signaling via PI3K isoforms beta and gamma is required for platelet ADP receptor function in dynamic thrombus stabilization.

Cosemans JM, Munnix IC, Wetzker R, Heller R, Jackson SP, Heemskerk JW. Cosemans JM, et al. Among authors: heemskerk jw. Blood. 2006 Nov 1;108(9):3045-52. doi: 10.1182/blood-2006-03-006338. Epub 2006 Jul 13. Blood. 2006. PMID: 16840732 Free article.

2

Collagen but not fibrinogen surfaces induce bleb formation, exposure of phosphatidylserine, and procoagulant activity of adherent platelets: evidence for regulation by protein tyrosine kinase-dependent Ca2+ responses.

Heemskerk JW, Vuist WM, Feijge MA, Reutelingsperger CP, Lindhout T. Heemskerk JW, et al. Blood. 1997 Oct 1;90(7):2615-25. Blood. 1997. PMID: 9326228 Free article.

3

Overexpression of the platelet P2X1 ion channel in transgenic mice generates a novel prothrombotic phenotype.

Oury C, Kuijpers MJ, Toth-Zsamboki E, Bonnefoy A, Danloy S, Vreys I, Feijge MA, De Vos R, Vermylen J, Heemskerk JW, Hoylaerts MF. Oury C, et al. Among authors: heemskerk jw. Blood. 2003 May 15;101(10):3969-76. doi: 10.1182/blood-2002-10-3215. Epub 2003 Jan 9. Blood. 2003. PMID: 12521992 Free article.

4

Real-time detection of activation patterns in individual platelets during thromboembolism in vivo: differences between thrombus growth and embolus formation.

van Gestel MA, Heemskerk JW, Slaaf DW, Heijnen VV, Sage SO, Reneman RS, oude Egbrink MG. van Gestel MA, et al. Among authors: heemskerk jw. J Vasc Res. 2002 Nov-Dec;39(6):534-43. doi: 10.1159/000067208. J Vasc Res. 2002. PMID: 12566979

5

In vivo blockade of platelet ADP receptor P2Y12 reduces embolus and thrombus formation but not thrombus stability.

van Gestel MA, Heemskerk JW, Slaaf DW, Heijnen VV, Reneman RS, oude Egbrink MG. van Gestel MA, et al. Among authors: heemskerk jw. Arterioscler Thromb Vasc Biol. 2003 Mar 1;23(3):518-23. doi: 10.1161/01.ATV.0000057809.32354.22. Epub 2003 Jan 23. Arterioscler Thromb Vasc Biol. 2003. PMID: 12615691

6

Store-mediated calcium entry in the regulation of phosphatidylserine exposure in blood cells from Scott patients.

Munnix IC, Harmsma M, Giddings JC, Collins PW, Feijge MA, Comfurius P, Heemskerk JW, Bevers EM. Munnix IC, et al. Among authors: heemskerk jw. Thromb Haemost. 2003 Apr;89(4):687-95. Thromb Haemost. 2003. PMID: 12669124

7

Platelet receptor interplay regulates collagen-induced thrombus formation in flowing human blood.

Siljander PR, Munnix IC, Smethurst PA, Deckmyn H, Lindhout T, Ouwehand WH, Farndale RW, Heemskerk JW. Siljander PR, et al. Among authors: heemskerk jw. Blood. 2004 Feb 15;103(4):1333-41. doi: 10.1182/blood-2003-03-0889. Epub 2003 Oct 16. Blood. 2004. PMID: 14563646 Free article.

8

Contribution of platelet glycoprotein VI to the thrombogenic effect of collagens in fibrous atherosclerotic lesions.

Cosemans JM, Kuijpers MJ, Lecut C, Loubele ST, Heeneman S, Jandrot-Perrus M, Heemskerk JW. Cosemans JM, et al. Among authors: heemskerk jw. Atherosclerosis. 2005 Jul;181(1):19-27. doi: 10.1016/j.atherosclerosis.2004.12.037. Epub 2005 Feb 12. Atherosclerosis. 2005. PMID: 15939050

9

Platelet P2Y12 receptors enhance signalling towards procoagulant activity and thrombin generation. A study with healthy subjects and patients at thrombotic risk.

van der Meijden PE, Feijge MA, Giesen PL, Huijberts M, van Raak LP, Heemskerk JW. van der Meijden PE, et al. Among authors: heemskerk jw. Thromb Haemost. 2005 Jun;93(6):1128-36. doi: 10.1160/TH04-09-0597. Thromb Haemost. 2005. PMID: 15968399

10

Platelet collagen receptors and coagulation. A characteristic platelet response as possible target for antithrombotic treatment.

Heemskerk JW, Kuijpers MJ, Munnix IC, Siljander PR. Heemskerk JW, et al. Trends Cardiovasc Med. 2005 Apr;15(3):86-92. doi: 10.1016/j.tcm.2005.03.003. Trends Cardiovasc Med. 2005. PMID: 16039967 Review.

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