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A highly stable polyethylene glycol-conjugated human single-chain antibody neutralizing granulocyte-macrophage colony stimulating factor at low nanomolar concentration.
Krinner EM, Hepp J, Hoffmann P, Bruckmaier S, Petersen L, Petsch S, Parr L, Schuster I, Mangold S, Lorenczewski G, Lutterbüse P, Buziol S, Hochheim I, Volkland J, Mølhøj M, Sriskandarajah M, Strasser M, Itin C, Wolf A, Basu A, Yang K, Filpula D, Sørensen P, Kufer P, Baeuerle P, Raum T. Krinner EM, et al. Protein Eng Des Sel. 2006 Oct;19(10):461-70. doi: 10.1093/protein/gzl031. Epub 2006 Jul 25. Protein Eng Des Sel. 2006. PMID: 16868004