S-Adenosylhomocysteine hydrolase (AdoHcyase) deficiency: enzymatic capabilities of human AdoHcyase are highly effected by changes to codon 89 and its surrounding residues.
Beluzić R, Cuk M, Pavkov T, Barić I, Vugrek O.
Beluzić R, et al. Among authors: pavkov t.
Biochem Biophys Res Commun. 2008 Mar 28;368(1):30-6. doi: 10.1016/j.bbrc.2008.01.042. Epub 2008 Jan 22.
Biochem Biophys Res Commun. 2008.
PMID: 18211827
Accordingly, we have proven the Y143C mutation to be highly inactivating [R. Beluzic, M. Cuk, T. Pavkov, K. Fumic, I. Baric, S.H. Mudd, I. Jurak, O. Vugrek, A single mutation at tyrosine 143 of human S-adenosylhomocysteine hydrolase renders the enzyme thermosensitiv …
Accordingly, we have proven the Y143C mutation to be highly inactivating [R. Beluzic, M. Cuk, T. Pavkov, K. Fumic, I. Baric, S …