Ahrens I - Search Results

1

A novel functional role for the highly conserved alpha-subunit KVGFFKR motif distinct from integrin alphaIIbbeta3 activation processes.

Aylward K, Meade G, Ahrens I, Devocelle M, Moran N. Aylward K, et al. Among authors: ahrens i. J Thromb Haemost. 2006 Aug;4(8):1804-12. doi: 10.1111/j.1538-7836.2006.02041.x. J Thromb Haemost. 2006. PMID: 16879224 Free article.

2

Evidence for a differential functional regulation of the two beta(3)-integrins alpha(V)beta(3) and alpha(IIb)beta(3).

Ahrens IG, Moran N, Aylward K, Meade G, Moser M, Assefa D, Fitzgerald DJ, Bode C, Peter K. Ahrens IG, et al. Exp Cell Res. 2006 Apr 1;312(6):925-37. doi: 10.1016/j.yexcr.2005.11.036. Epub 2006 Jan 23. Exp Cell Res. 2006. PMID: 16434034

3

Conformation-specific blockade of the integrin GPIIb/IIIa: a novel antiplatelet strategy that selectively targets activated platelets.

Schwarz M, Meade G, Stoll P, Ylanne J, Bassler N, Chen YC, Hagemeyer CE, Ahrens I, Moran N, Kenny D, Fitzgerald D, Bode C, Peter K. Schwarz M, et al. Among authors: ahrens i. Circ Res. 2006 Jul 7;99(1):25-33. doi: 10.1161/01.RES.0000232317.84122.0c. Epub 2006 Jun 15. Circ Res. 2006. PMID: 16778135

4

Therapeutic integrin inhibition: allosteric and activation-specific inhibition strategies may surpass the initial ligand-mimetic strategies.

Ahrens I, Peter K. Ahrens I, et al. Thromb Haemost. 2008 May;99(5):803-4. doi: 10.1160/TH08-03-0194. Thromb Haemost. 2008. PMID: 18449408 No abstract available.

5

Distinct roles of ligand affinity and cytoskeletal anchorage in alphaIIbbeta3 (GP IIb/IIIa)-mediated cell aggregation and adhesion.

Peter K, Ahrens I, Schwarz M, Bode C, Ylänne J. Peter K, et al. Among authors: ahrens i. Platelets. 2004 Nov;15(7):427-38. doi: 10.1080/09587100410001723179. Platelets. 2004. PMID: 15745314 Free article.

6

A mechanistic model for paradoxical platelet activation by ligand-mimetic alphaIIb beta3 (GPIIb/IIIa) antagonists.

Bassler N, Loeffler C, Mangin P, Yuan Y, Schwarz M, Hagemeyer CE, Eisenhardt SU, Ahrens I, Bode C, Jackson SP, Peter K. Bassler N, et al. Among authors: ahrens i. Arterioscler Thromb Vasc Biol. 2007 Mar;27(3):e9-15. doi: 10.1161/01.ATV.0000255307.65939.59. Epub 2006 Dec 14. Arterioscler Thromb Vasc Biol. 2007. PMID: 17170374

7

HMGB1 binds to activated platelets via the receptor for advanced glycation end products and is present in platelet rich human coronary artery thrombi.

Ahrens I, Chen YC, Topcic D, Bode M, Haenel D, Hagemeyer CE, Seeba H, Duerschmied D, Bassler N, Jandeleit-Dahm KA, Sweet MJ, Agrotis A, Bobik A, Peter K. Ahrens I, et al. Thromb Haemost. 2015 Nov;114(5):994-1003. doi: 10.1160/TH14-12-1073. Epub 2015 Jul 23. Thromb Haemost. 2015. PMID: 26202300

8

Immune functions of platelets.

Duerschmied D, Bode C, Ahrens I. Duerschmied D, et al. Among authors: ahrens i. Thromb Haemost. 2014 Oct;112(4):678-91. doi: 10.1160/TH14-02-0146. Epub 2014 Sep 11. Thromb Haemost. 2014. PMID: 25209670 Review.

9

Bleeding Complications Drive In-Hospital Mortality of Patients with Atrial Fibrillation after Transcatheter Aortic Valve Replacement.

Lother A, Kaier K, Ahrens I, Bothe W, Wolf D, Zehender M, Bode C, von Zur Mühlen C, Stachon P. Lother A, et al. Among authors: ahrens i. Thromb Haemost. 2020 Nov;120(11):1580-1586. doi: 10.1055/s-0040-1715833. Epub 2020 Aug 22. Thromb Haemost. 2020. PMID: 32828074

10

Inhibition of platelet activation and aggregation.

Ahrens I, Bode C, Peter K. Ahrens I, et al. Handb Exp Pharmacol. 2005;(170):443-62. doi: 10.1007/3-540-27661-0_16. Handb Exp Pharmacol. 2005. PMID: 16596810 Review.

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