Lourenço FC - Search Results

1

Anaplastic lymphoma kinase is a dependence receptor whose proapoptotic functions are activated by caspase cleavage.

Mourali J, Bénard A, Lourenço FC, Monnet C, Greenland C, Moog-Lutz C, Racaud-Sultan C, Gonzalez-Dunia D, Vigny M, Mehlen P, Delsol G, Allouche M. Mourali J, et al. Among authors: lourenco fc. Mol Cell Biol. 2006 Aug;26(16):6209-22. doi: 10.1128/MCB.01515-05. Mol Cell Biol. 2006. PMID: 16880530 Free PMC article.

2

Proapoptotic function of the MET tyrosine kinase receptor through caspase cleavage.

Tulasne D, Deheuninck J, Lourenco FC, Lamballe F, Ji Z, Leroy C, Puchois E, Moumen A, Maina F, Mehlen P, Fafeur V. Tulasne D, et al. Among authors: lourenco fc. Mol Cell Biol. 2004 Dec;24(23):10328-39. doi: 10.1128/MCB.24.23.10328-10339.2004. Mol Cell Biol. 2004. PMID: 15542841 Free PMC article.

3

The dependence receptor UNC5H2 mediates apoptosis through DAP-kinase.

Llambi F, Lourenço FC, Gozuacik D, Guix C, Pays L, Del Rio G, Kimchi A, Mehlen P. Llambi F, et al. Among authors: lourenco fc. EMBO J. 2005 Mar 23;24(6):1192-201. doi: 10.1038/sj.emboj.7600584. Epub 2005 Feb 24. EMBO J. 2005. PMID: 15729359 Free PMC article.

4

Netrin-1 interacts with amyloid precursor protein and regulates amyloid-beta production.

Lourenço FC, Galvan V, Fombonne J, Corset V, Llambi F, Müller U, Bredesen DE, Mehlen P. Lourenço FC, et al. Cell Death Differ. 2009 May;16(5):655-63. doi: 10.1038/cdd.2008.191. Epub 2009 Jan 16. Cell Death Differ. 2009. PMID: 19148186 Free PMC article.

5

p53-mediated transcriptional regulation and activation of the actin cytoskeleton regulatory RhoC to LIMK2 signaling pathway promotes cell survival.

Croft DR, Crighton D, Samuel MS, Lourenco FC, Munro J, Wood J, Bensaad K, Vousden KH, Sansom OJ, Ryan KM, Olson MF. Croft DR, et al. Among authors: lourenco fc. Cell Res. 2011 Apr;21(4):666-82. doi: 10.1038/cr.2010.154. Epub 2010 Nov 16. Cell Res. 2011. PMID: 21079653 Free PMC article.

6

LIM kinase inhibitors disrupt mitotic microtubule organization and impair tumor cell proliferation.

Mardilovich K, Baugh M, Crighton D, Kowalczyk D, Gabrielsen M, Munro J, Croft DR, Lourenco F, James D, Kalna G, McGarry L, Rath O, Shanks E, Garnett MJ, McDermott U, Brookfield J, Charles M, Hammonds T, Olson MF. Mardilovich K, et al. Oncotarget. 2015 Nov 17;6(36):38469-86. doi: 10.18632/oncotarget.6288. Oncotarget. 2015. PMID: 26540348 Free PMC article.

7

K-Ras mediated murine epidermal tumorigenesis is dependent upon and associated with elevated Rac1 activity.

Samuel MS, Lourenço FC, Olson MF. Samuel MS, et al. Among authors: lourenco fc. PLoS One. 2011 Feb 15;6(2):e17143. doi: 10.1371/journal.pone.0017143. PLoS One. 2011. PMID: 21358804 Free PMC article.

8

Reduced LIMK2 expression in colorectal cancer reflects its role in limiting stem cell proliferation.

Lourenço FC, Munro J, Brown J, Cordero J, Stefanatos R, Strathdee K, Orange C, Feller SM, Sansom OJ, Vidal M, Murray GI, Olson MF. Lourenço FC, et al. Gut. 2014 Mar;63(3):480-93. doi: 10.1136/gutjnl-2012-303883. Epub 2013 Apr 12. Gut. 2014. PMID: 23585469 Free PMC article.

9

Stem cell functionality is microenvironmentally defined during tumour expansion and therapy response in colon cancer.

Lenos KJ, Miedema DM, Lodestijn SC, Nijman LE, van den Bosch T, Romero Ros X, Lourenço FC, Lecca MC, van der Heijden M, van Neerven SM, van Oort A, Leveille N, Adam RS, de Sousa E Melo F, Otten J, Veerman P, Hypolite G, Koens L, Lyons SK, Stassi G, Winton DJ, Medema JP, Morrissey E, Bijlsma MF, Vermeulen L. Lenos KJ, et al. Among authors: lourenco fc. Nat Cell Biol. 2018 Oct;20(10):1193-1202. doi: 10.1038/s41556-018-0179-z. Epub 2018 Sep 3. Nat Cell Biol. 2018. PMID: 30177776 Free PMC article.

10

Quantifying Microsatellite Mutation Rates from Intestinal Stem Cell Dynamics in Msh2-Deficient Murine Epithelium.

Christopher J, Thorsen AS, Abujudeh S, Lourenço FC, Kemp R, Potter PK, Morrissey E, Hazelwood L, Winton DJ. Christopher J, et al. Among authors: lourenco fc. Genetics. 2019 Jul;212(3):655-665. doi: 10.1534/genetics.119.302268. Epub 2019 May 24. Genetics. 2019. PMID: 31126976 Free PMC article.

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