Balzarini J - Search Results

1

Mutational pathways, resistance profile, and side effects of cyanovirin relative to human immunodeficiency virus type 1 strains with N-glycan deletions in their gp120 envelopes.

Balzarini J, Van Laethem K, Peumans WJ, Van Damme EJ, Bolmstedt A, Gago F, Schols D. Balzarini J, et al. J Virol. 2006 Sep;80(17):8411-21. doi: 10.1128/JVI.00369-06. J Virol. 2006. PMID: 16912292 Free PMC article.

2

Profile of resistance of human immunodeficiency virus to mannose-specific plant lectins.

Balzarini J, Van Laethem K, Hatse S, Vermeire K, De Clercq E, Peumans W, Van Damme E, Vandamme AM, Bölmstedt A, Schols D. Balzarini J, et al. J Virol. 2004 Oct;78(19):10617-27. doi: 10.1128/JVI.78.19.10617-10627.2004. J Virol. 2004. PMID: 15367629 Free PMC article.

3

Marked depletion of glycosylation sites in HIV-1 gp120 under selection pressure by the mannose-specific plant lectins of Hippeastrum hybrid and Galanthus nivalis.

Balzarini J, Van Laethem K, Hatse S, Froeyen M, Van Damme E, Bolmstedt A, Peumans W, De Clercq E, Schols D. Balzarini J, et al. Mol Pharmacol. 2005 May;67(5):1556-65. doi: 10.1124/mol.104.005082. Epub 2005 Feb 17. Mol Pharmacol. 2005. PMID: 15718224

4

Carbohydrate-binding agents cause deletions of highly conserved glycosylation sites in HIV GP120: a new therapeutic concept to hit the achilles heel of HIV.

Balzarini J, Van Laethem K, Hatse S, Froeyen M, Peumans W, Van Damme E, Schols D. Balzarini J, et al. J Biol Chem. 2005 Dec 9;280(49):41005-14. doi: 10.1074/jbc.M508801200. Epub 2005 Sep 23. J Biol Chem. 2005. PMID: 16183648 Free article.

Hippeastrum hybrid and Galanthus nivalis agglutinin) or prokaryotes (i.e. cyanovirin-N) inhibit human immunodeficiency virus (HIV) replication and select for drug-resistant viruses that show profound deletion of N-glycosylation sites in the GP120 envelope (Balzarini, J …

Hippeastrum hybrid and Galanthus nivalis agglutinin) or prokaryotes (i.e. cyanovirin-N) inhibit human immunodeficiency virus (HIV) replicati …

5

Sugar-binding proteins potently inhibit dendritic cell human immunodeficiency virus type 1 (HIV-1) infection and dendritic-cell-directed HIV-1 transfer.

Turville SG, Vermeire K, Balzarini J, Schols D. Turville SG, et al. Among authors: balzarini j. J Virol. 2005 Nov;79(21):13519-27. doi: 10.1128/JVI.79.21.13519-13527.2005. J Virol. 2005. PMID: 16227272 Free PMC article.

6

Pradimicin A, a carbohydrate-binding nonpeptidic lead compound for treatment of infections with viruses with highly glycosylated envelopes, such as human immunodeficiency virus.

Balzarini J, Van Laethem K, Daelemans D, Hatse S, Bugatti A, Rusnati M, Igarashi Y, Oki T, Schols D. Balzarini J, et al. J Virol. 2007 Jan;81(1):362-73. doi: 10.1128/JVI.01404-06. Epub 2006 Oct 18. J Virol. 2007. PMID: 17050611 Free PMC article.

7

Resistance of HIV-1 to the broadly HIV-1-neutralizing, anti-carbohydrate antibody 2G12.

Huskens D, Van Laethem K, Vermeire K, Balzarini J, Schols D. Huskens D, et al. Among authors: balzarini j. Virology. 2007 Apr 10;360(2):294-304. doi: 10.1016/j.virol.2006.10.027. Epub 2006 Nov 21. Virology. 2007. PMID: 17123566 Free article.

8

Entry of hepatitis C virus and human immunodeficiency virus is selectively inhibited by carbohydrate-binding agents but not by polyanions.

Bertaux C, Daelemans D, Meertens L, Cormier EG, Reinus JF, Peumans WJ, Van Damme EJ, Igarashi Y, Oki T, Schols D, Dragic T, Balzarini J. Bertaux C, et al. Among authors: balzarini j. Virology. 2007 Sep 15;366(1):40-50. doi: 10.1016/j.virol.2007.04.008. Epub 2007 May 11. Virology. 2007. PMID: 17498767 Free article.

9

Glycan deletions in the HIV-1 gp120 V1/V2 domain compromise viral infectivity, sensitize the mutant virus strains to carbohydrate-binding agents and represent a specific target for therapeutic intervention.

Auwerx J, François KO, Covens K, Van Laethem K, Balzarini J. Auwerx J, et al. Among authors: balzarini j. Virology. 2008 Dec 5;382(1):10-9. doi: 10.1016/j.virol.2008.09.010. Epub 2008 Oct 19. Virology. 2008. PMID: 18930512 Free article.

10

Antiviral activity of carbohydrate-binding agents and the role of DC-SIGN in dengue virus infection.

Alen MM, Kaptein SJ, De Burghgraeve T, Balzarini J, Neyts J, Schols D. Alen MM, et al. Among authors: balzarini j. Virology. 2009 Apr 25;387(1):67-75. doi: 10.1016/j.virol.2009.01.043. Epub 2009 Mar 4. Virology. 2009. PMID: 19264337 Free article.

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