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Mannose-specific plant lectins from the Amaryllidaceae family qualify as efficient microbicides for prevention of human immunodeficiency virus infection.
Balzarini J, Hatse S, Vermeire K, Princen K, Aquaro S, Perno CF, De Clercq E, Egberink H, Vanden Mooter G, Peumans W, Van Damme E, Schols D. Balzarini J, et al. Antimicrob Agents Chemother. 2004 Oct;48(10):3858-70. doi: 10.1128/AAC.48.10.3858-3870.2004. Antimicrob Agents Chemother. 2004. PMID: 15388446 Free PMC article.
The mannose-specific plant lectins from Cymbidium hybrid and Epipactis helleborine and the (N-acetylglucosamine)n-specific plant lectin from Urtica dioica are potent and selective inhibitors of human immunodeficiency virus and cytomegalovirus replication in vitro.
Balzarini J, Neyts J, Schols D, Hosoya M, Van Damme E, Peumans W, De Clercq E. Balzarini J, et al. Antiviral Res. 1992 Jun;18(2):191-207. doi: 10.1016/0166-3542(92)90038-7. Antiviral Res. 1992. PMID: 1329650
Carbohydrate-binding agents (CBAs) inhibit HIV-1 infection in human primary monocyte-derived macrophages (MDMs) and efficiently prevent MDM-directed viral capture and subsequent transmission to CD4+ T lymphocytes.
Pollicita M, Schols D, Aquaro S, Peumans WJ, Van Damme EJ, Perno CF, Balzarini J. Pollicita M, et al. Among authors: peumans wj. Virology. 2008 Jan 20;370(2):382-91. doi: 10.1016/j.virol.2007.08.033. Epub 2007 Oct 24. Virology. 2008. PMID: 17928023 Free article.
266 results