Astle MV - Search Results

1

Regulation of phosphoinositide signaling by the inositol polyphosphate 5-phosphatases.

Astle MV, Seaton G, Davies EM, Fedele CG, Rahman P, Arsala L, Mitchell CA. Astle MV, et al. IUBMB Life. 2006 Aug;58(8):451-6. doi: 10.1080/15216540600871159. IUBMB Life. 2006. PMID: 16916781 Free article. Review.

2

The SH2 domain containing inositol polyphosphate 5-phosphatase-2: SHIP2.

Dyson JM, Kong AM, Wiradjaja F, Astle MV, Gurung R, Mitchell CA. Dyson JM, et al. Among authors: astle mv. Int J Biochem Cell Biol. 2005 Nov;37(11):2260-5. doi: 10.1016/j.biocel.2005.05.003. Int J Biochem Cell Biol. 2005. PMID: 15964236 Review.

3

The inositol polyphosphate 5-phosphatase, PIPP, Is a novel regulator of phosphoinositide 3-kinase-dependent neurite elongation.

Ooms LM, Fedele CG, Astle MV, Ivetac I, Cheung V, Pearson RB, Layton MJ, Forrai A, Nandurkar HH, Mitchell CA. Ooms LM, et al. Among authors: astle mv. Mol Biol Cell. 2006 Feb;17(2):607-22. doi: 10.1091/mbc.e05-05-0469. Epub 2005 Nov 9. Mol Biol Cell. 2006. PMID: 16280363 Free PMC article.

4

The inositol polyphosphate 5-phosphatases: traffic controllers, waistline watchers and tumour suppressors?

Astle MV, Horan KA, Ooms LM, Mitchell CA. Astle MV, et al. Biochem Soc Symp. 2007;(74):161-81. doi: 10.1042/BSS0740161. Biochem Soc Symp. 2007. PMID: 17233589 Review.

5

Identification of a proline-rich inositol polyphosphate 5-phosphatase (PIPP)•collapsin response mediator protein 2 (CRMP2) complex that regulates neurite elongation.

Astle MV, Ooms LM, Cole AR, Binge LC, Dyson JM, Layton MJ, Petratos S, Sutherland C, Mitchell CA. Astle MV, et al. J Biol Chem. 2011 Jul 1;286(26):23407-18. doi: 10.1074/jbc.M110.214247. Epub 2011 May 6. J Biol Chem. 2011. PMID: 21550974 Free PMC article.

6

P-Rex1 - a multidomain protein that regulates neurite differentiation.

Waters JE, Astle MV, Ooms LM, Balamatsias D, Gurung R, Mitchell CA. Waters JE, et al. Among authors: astle mv. J Cell Sci. 2008 Sep 1;121(Pt 17):2892-903. doi: 10.1242/jcs.030353. Epub 2008 Aug 12. J Cell Sci. 2008. PMID: 18697831

7

AKT promotes rRNA synthesis and cooperates with c-MYC to stimulate ribosome biogenesis in cancer.

Chan JC, Hannan KM, Riddell K, Ng PY, Peck A, Lee RS, Hung S, Astle MV, Bywater M, Wall M, Poortinga G, Jastrzebski K, Sheppard KE, Hemmings BA, Hall MN, Johnstone RW, McArthur GA, Hannan RD, Pearson RB. Chan JC, et al. Among authors: astle mv. Sci Signal. 2011 Aug 30;4(188):ra56. doi: 10.1126/scisignal.2001754. Sci Signal. 2011. PMID: 21878679

8

AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: implications for targeting mTOR during malignancy.

Astle MV, Hannan KM, Ng PY, Lee RS, George AJ, Hsu AK, Haupt Y, Hannan RD, Pearson RB. Astle MV, et al. Oncogene. 2012 Apr 12;31(15):1949-62. doi: 10.1038/onc.2011.394. Epub 2011 Sep 12. Oncogene. 2012. PMID: 21909130 Free PMC article.

9

The mTORC1 inhibitor everolimus prevents and treats Eμ-Myc lymphoma by restoring oncogene-induced senescence.

Wall M, Poortinga G, Stanley KL, Lindemann RK, Bots M, Chan CJ, Bywater MJ, Kinross KM, Astle MV, Waldeck K, Hannan KM, Shortt J, Smyth MJ, Lowe SW, Hannan RD, Pearson RB, Johnstone RW, McArthur GA. Wall M, et al. Among authors: astle mv. Cancer Discov. 2013 Jan;3(1):82-95. doi: 10.1158/2159-8290.CD-12-0404. Epub 2012 Dec 14. Cancer Discov. 2013. PMID: 23242809 Free PMC article.

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