Westwood IM - Search Results

1

Structure and mechanism of arylamine N-acetyltransferases.

Westwood IM, Kawamura A, Fullam E, Russell AJ, Davies SG, Sim E. Westwood IM, et al. Curr Top Med Chem. 2006;6(15):1641-54. doi: 10.2174/156802606778108979. Curr Top Med Chem. 2006. PMID: 16918475 Review.

2

Arylamine N-acetyltransferases.

Sim E, Westwood I, Fullam E. Sim E, et al. Expert Opin Drug Metab Toxicol. 2007 Apr;3(2):169-84. doi: 10.1517/17425255.3.2.169. Expert Opin Drug Metab Toxicol. 2007. PMID: 17428149 Review.

3

Arylamine N-acetyltransferases in mycobacteria.

Sim E, Sandy J, Evangelopoulos D, Fullam E, Bhakta S, Westwood I, Krylova A, Lack N, Noble M. Sim E, et al. Curr Drug Metab. 2008 Jul;9(6):510-9. doi: 10.2174/138920008784892100. Curr Drug Metab. 2008. PMID: 18680471 Free PMC article. Review.

4

Arylamine N-acetyltransferases: structural and functional implications of polymorphisms.

Sim E, Lack N, Wang CJ, Long H, Westwood I, Fullam E, Kawamura A. Sim E, et al. Toxicology. 2008 Dec 30;254(3):170-83. doi: 10.1016/j.tox.2008.08.022. Epub 2008 Sep 12. Toxicology. 2008. PMID: 18852012 Review.

5

Comparison of the Arylamine N-acetyltransferase from Mycobacterium marinum and Mycobacterium tuberculosis.

Fullam E, Kawamura A, Wilkinson H, Abuhammad A, Westwood I, Sim E. Fullam E, et al. Protein J. 2009 Aug;28(6):281-93. doi: 10.1007/s10930-009-9193-0. Protein J. 2009. PMID: 19636684

6

Design, synthesis and structure-activity relationships of 3,5-diaryl-1H-pyrazoles as inhibitors of arylamine N-acetyltransferase.

Fullam E, Talbot J, Abuhammed A, Westwood I, Davies SG, Russell AJ, Sim E. Fullam E, et al. Bioorg Med Chem Lett. 2013 May 1;23(9):2759-64. doi: 10.1016/j.bmcl.2013.02.052. Epub 2013 Feb 22. Bioorg Med Chem Lett. 2013. PMID: 23518278

7

Synthesis and in vitro evaluation of novel small molecule inhibitors of bacterial arylamine N-acetyltransferases (NATs).

Brooke EW, Davies SG, Mulvaney AW, Okada M, Pompeo F, Sim E, Vickers RJ, Westwood IM. Brooke EW, et al. Among authors: westwood im. Bioorg Med Chem Lett. 2003 Aug 4;13(15):2527-30. doi: 10.1016/s0960-894x(03)00484-0. Bioorg Med Chem Lett. 2003. PMID: 12852958

8

Kinetic characterisation of arylamine N-acetyltransferase from Pseudomonas aeruginosa.

Westwood IM, Sim E. Westwood IM, et al. BMC Biochem. 2007 Mar 20;8:3. doi: 10.1186/1471-2091-8-3. BMC Biochem. 2007. PMID: 17374145 Free PMC article.

9

Divergence of cofactor recognition across evolution: coenzyme A binding in a prokaryotic arylamine N-acetyltransferase.

Fullam E, Westwood IM, Anderton MC, Lowe ED, Sim E, Noble ME. Fullam E, et al. Among authors: westwood im. J Mol Biol. 2008 Jan 4;375(1):178-91. doi: 10.1016/j.jmb.2007.10.019. Epub 2007 Oct 13. J Mol Biol. 2008. PMID: 18005984

10

Selective small molecule inhibitors of the potential breast cancer marker, human arylamine N-acetyltransferase 1, and its murine homologue, mouse arylamine N-acetyltransferase 2.

Russell AJ, Westwood IM, Crawford MH, Robinson J, Kawamura A, Redfield C, Laurieri N, Lowe ED, Davies SG, Sim E. Russell AJ, et al. Among authors: westwood im. Bioorg Med Chem. 2009 Jan 15;17(2):905-18. doi: 10.1016/j.bmc.2008.11.032. Epub 2008 Nov 19. Bioorg Med Chem. 2009. PMID: 19059786

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