Xu H - Search Results

1

Pathological and physiological functions of presenilins.

Vetrivel KS, Zhang YW, Xu H, Thinakaran G. Vetrivel KS, et al. Among authors: xu h. Mol Neurodegener. 2006 Jun 12;1:4. doi: 10.1186/1750-1326-1-4. Mol Neurodegener. 2006. PMID: 16930451 Free PMC article.

2

Presenilin 1 is required for maturation and cell surface accumulation of nicastrin.

Leem JY, Vijayan S, Han P, Cai D, Machura M, Lopes KO, Veselits ML, Xu H, Thinakaran G. Leem JY, et al. Among authors: xu h. J Biol Chem. 2002 May 24;277(21):19236-40. doi: 10.1074/jbc.C200148200. Epub 2002 Apr 9. J Biol Chem. 2002. PMID: 11943765 Free article.

3

Presenilin-1 regulates intracellular trafficking and cell surface delivery of beta-amyloid precursor protein.

Cai D, Leem JY, Greenfield JP, Wang P, Kim BS, Wang R, Lopes KO, Kim SH, Zheng H, Greengard P, Sisodia SS, Thinakaran G, Xu H. Cai D, et al. Among authors: xu h. J Biol Chem. 2003 Jan 31;278(5):3446-54. doi: 10.1074/jbc.M209065200. Epub 2002 Nov 14. J Biol Chem. 2003. PMID: 12435726 Free article.

4

A role for presenilin 1 in regulating the delivery of amyloid precursor protein to the cell surface.

Leem JY, Saura CA, Pietrzik C, Christianson J, Wanamaker C, King LT, Veselits ML, Tomita T, Gasparini L, Iwatsubo T, Xu H, Green WN, Koo EH, Thinakaran G. Leem JY, et al. Among authors: xu h. Neurobiol Dis. 2002 Oct;11(1):64-82. doi: 10.1006/nbdi.2002.0546. Neurobiol Dis. 2002. PMID: 12460547

5

PEN-2 and APH-1 coordinately regulate proteolytic processing of presenilin 1.

Luo WJ, Wang H, Li H, Kim BS, Shah S, Lee HJ, Thinakaran G, Kim TW, Yu G, Xu H. Luo WJ, et al. Among authors: xu h. J Biol Chem. 2003 Mar 7;278(10):7850-4. doi: 10.1074/jbc.C200648200. Epub 2003 Jan 8. J Biol Chem. 2003. PMID: 12522139 Free article.

6

Presenilins and gamma-secretase inhibitors affect intracellular trafficking and cell surface localization of the gamma-secretase complex components.

Wang H, Luo WJ, Zhang YW, Li YM, Thinakaran G, Greengard P, Xu H. Wang H, et al. Among authors: xu h. J Biol Chem. 2004 Sep 24;279(39):40560-6. doi: 10.1074/jbc.M404345200. Epub 2004 Jul 7. J Biol Chem. 2004. PMID: 15247291 Free article.

7

Association of gamma-secretase with lipid rafts in post-Golgi and endosome membranes.

Vetrivel KS, Cheng H, Lin W, Sakurai T, Li T, Nukina N, Wong PC, Xu H, Thinakaran G. Vetrivel KS, et al. Among authors: xu h. J Biol Chem. 2004 Oct 22;279(43):44945-54. doi: 10.1074/jbc.M407986200. Epub 2004 Aug 17. J Biol Chem. 2004. PMID: 15322084 Free PMC article.

8

Nicastrin is critical for stability and trafficking but not association of other presenilin/gamma-secretase components.

Zhang YW, Luo WJ, Wang H, Lin P, Vetrivel KS, Liao F, Li F, Wong PC, Farquhar MG, Thinakaran G, Xu H. Zhang YW, et al. Among authors: xu h. J Biol Chem. 2005 Apr 29;280(17):17020-6. doi: 10.1074/jbc.M409467200. Epub 2005 Feb 11. J Biol Chem. 2005. PMID: 15711015 Free PMC article.

9

Suppression of cyclin-dependent kinase 5 activation by amyloid precursor protein: a novel excitoprotective mechanism involving modulation of tau phosphorylation.

Han P, Dou F, Li F, Zhang X, Zhang YW, Zheng H, Lipton SA, Xu H, Liao FF. Han P, et al. Among authors: xu h. J Neurosci. 2005 Dec 14;25(50):11542-52. doi: 10.1523/JNEUROSCI.3831-05.2005. J Neurosci. 2005. PMID: 16354912 Free PMC article.

10

Transcriptional regulation of PEN-2, a key component of the gamma-secretase complex, by CREB.

Wang R, Zhang YW, Sun P, Liu R, Zhang X, Zhang X, Xia K, Xia J, Xu H, Zhang Z. Wang R, et al. Among authors: xu h. Mol Cell Biol. 2006 Feb;26(4):1347-54. doi: 10.1128/MCB.26.4.1347-1354.2006. Mol Cell Biol. 2006. PMID: 16449647 Free PMC article.

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