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Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis.
Bachoo RM, Maher EA, Ligon KL, Sharpless NE, Chan SS, You MJ, Tang Y, DeFrances J, Stover E, Weissleder R, Rowitch DH, Louis DN, DePinho RA. Bachoo RM, et al. Among authors: sharpless ne. Cancer Cell. 2002 Apr;1(3):269-77. doi: 10.1016/s1535-6108(02)00046-6. Cancer Cell. 2002. PMID: 12086863 Free article.
Ink4a/Arf expression is a biomarker of aging.
Krishnamurthy J, Torrice C, Ramsey MR, Kovalev GI, Al-Regaiey K, Su L, Sharpless NE. Krishnamurthy J, et al. Among authors: sharpless ne. J Clin Invest. 2004 Nov;114(9):1299-307. doi: 10.1172/JCI22475. J Clin Invest. 2004. PMID: 15520862 Free PMC article.
Ink4a/Arf links senescence and aging.
Sharpless NE. Sharpless NE. Exp Gerontol. 2004 Nov-Dec;39(11-12):1751-9. doi: 10.1016/j.exger.2004.06.025. Exp Gerontol. 2004. PMID: 15582292 Review.
Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a.
Janzen V, Forkert R, Fleming HE, Saito Y, Waring MT, Dombkowski DM, Cheng T, DePinho RA, Sharpless NE, Scadden DT. Janzen V, et al. Among authors: sharpless ne. Nature. 2006 Sep 28;443(7110):421-6. doi: 10.1038/nature05159. Epub 2006 Sep 6. Nature. 2006. PMID: 16957735
The regulation of INK4/ARF in cancer and aging.
Kim WY, Sharpless NE. Kim WY, et al. Among authors: sharpless ne. Cell. 2006 Oct 20;127(2):265-75. doi: 10.1016/j.cell.2006.10.003. Cell. 2006. PMID: 17055429 Free article. Review.
197 results