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A heterozygous effect for PINK1 mutations in Parkinson's disease?
Abou-Sleiman PM, Muqit MM, McDonald NQ, Yang YX, Gandhi S, Healy DG, Harvey K, Harvey RJ, Deas E, Bhatia K, Quinn N, Lees A, Latchman DS, Wood NW. Abou-Sleiman PM, et al. Ann Neurol. 2006 Oct;60(4):414-9. doi: 10.1002/ana.20960. Ann Neurol. 2006. PMID: 16969854
Mutations in the gene LRRK2 encoding dardarin (PARK8) cause familial Parkinson's disease: clinical, pathological, olfactory and functional imaging and genetic data.
Khan NL, Jain S, Lynch JM, Pavese N, Abou-Sleiman P, Holton JL, Healy DG, Gilks WP, Sweeney MG, Ganguly M, Gibbons V, Gandhi S, Vaughan J, Eunson LH, Katzenschlager R, Gayton J, Lennox G, Revesz T, Nicholl D, Bhatia KP, Quinn N, Brooks D, Lees AJ, Davis MB, Piccini P, Singleton AB, Wood NW. Khan NL, et al. Brain. 2005 Dec;128(Pt 12):2786-96. doi: 10.1093/brain/awh667. Epub 2005 Nov 4. Brain. 2005. PMID: 16272164
DJ-1 mutations in Parkinson's disease.
Healy DG, Abou-Sleiman PM, Valente EM, Gilks WP, Bhatia K, Quinn N, Lees AJ, Wood NW. Healy DG, et al. J Neurol Neurosurg Psychiatry. 2004 Jan;75(1):144-5. J Neurol Neurosurg Psychiatry. 2004. PMID: 14707326 Free PMC article.
Tau gene and Parkinson's disease: a case-control study and meta-analysis.
Healy DG, Abou-Sleiman PM, Lees AJ, Casas JP, Quinn N, Bhatia K, Hingorani AD, Wood NW. Healy DG, et al. J Neurol Neurosurg Psychiatry. 2004 Jul;75(7):962-5. doi: 10.1136/jnnp.2003.026203. J Neurol Neurosurg Psychiatry. 2004. PMID: 15201350 Free PMC article.
Genetic approaches to solving common diseases.
Abou-Sleiman PM, Healy DG, Wood NW. Abou-Sleiman PM, et al. J Neurol. 2004 Oct;251(10):1169-72. doi: 10.1007/s00415-004-0518-9. J Neurol. 2004. PMID: 15503093 Review.
PINK1 (PARK6) associated Parkinson disease in Ireland.
Healy DG, Abou-Sleiman PM, Gibson JM, Ross OA, Jain S, Gandhi S, Gosal D, Muqit MM, Wood NW, Lynch T. Healy DG, et al. Neurology. 2004 Oct 26;63(8):1486-8. doi: 10.1212/01.wnl.0000142089.38301.8e. Neurology. 2004. PMID: 15505171
PINK1 protein in normal human brain and Parkinson's disease.
Gandhi S, Muqit MM, Stanyer L, Healy DG, Abou-Sleiman PM, Hargreaves I, Heales S, Ganguly M, Parsons L, Lees AJ, Latchman DS, Holton JL, Wood NW, Revesz T. Gandhi S, et al. Brain. 2006 Jul;129(Pt 7):1720-31. doi: 10.1093/brain/awl114. Epub 2006 May 15. Brain. 2006. PMID: 16702191
Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study.
Healy DG, Falchi M, O'Sullivan SS, Bonifati V, Durr A, Bressman S, Brice A, Aasly J, Zabetian CP, Goldwurm S, Ferreira JJ, Tolosa E, Kay DM, Klein C, Williams DR, Marras C, Lang AE, Wszolek ZK, Berciano J, Schapira AH, Lynch T, Bhatia KP, Gasser T, Lees AJ, Wood NW; International LRRK2 Consortium. Healy DG, et al. Lancet Neurol. 2008 Jul;7(7):583-90. doi: 10.1016/S1474-4422(08)70117-0. Epub 2008 Jun 6. Lancet Neurol. 2008. PMID: 18539534 Free PMC article.
44 results