Ray DM - Search Results

1

Activated human T lymphocytes express cyclooxygenase-2 and produce proadipogenic prostaglandins that drive human orbital fibroblast differentiation to adipocytes.

Feldon SE, O'loughlin CW, Ray DM, Landskroner-Eiger S, Seweryniak KE, Phipps RP. Feldon SE, et al. Among authors: ray dm. Am J Pathol. 2006 Oct;169(4):1183-93. doi: 10.2353/ajpath.2006.060434. Am J Pathol. 2006. PMID: 17003477 Free PMC article.

2

Human multiple myeloma cells express peroxisome proliferator-activated receptor gamma and undergo apoptosis upon exposure to PPARgamma ligands.

Ray DM, Bernstein SH, Phipps RP. Ray DM, et al. Clin Immunol. 2004 Nov;113(2):203-13. doi: 10.1016/j.clim.2004.06.011. Clin Immunol. 2004. PMID: 15451478

3

The peroxisome proliferator-activated receptor gamma (PPARgamma) ligands 15-deoxy-Delta12,14-prostaglandin J2 and ciglitazone induce human B lymphocyte and B cell lymphoma apoptosis by PPARgamma-independent mechanisms.

Ray DM, Akbiyik F, Phipps RP. Ray DM, et al. J Immunol. 2006 Oct 15;177(8):5068-76. doi: 10.4049/jimmunol.177.8.5068. J Immunol. 2006. PMID: 17015690

4

Human bone marrow megakaryocytes and platelets express PPARgamma, and PPARgamma agonists blunt platelet release of CD40 ligand and thromboxanes.

Akbiyik F, Ray DM, Gettings KF, Blumberg N, Francis CW, Phipps RP. Akbiyik F, et al. Among authors: ray dm. Blood. 2004 Sep 1;104(5):1361-8. doi: 10.1182/blood-2004-03-0926. Epub 2004 May 6. Blood. 2004. PMID: 15130939 Free article.

5

PPARgamma agonists inhibit TGF-beta induced pulmonary myofibroblast differentiation and collagen production: implications for therapy of lung fibrosis.

Burgess HA, Daugherty LE, Thatcher TH, Lakatos HF, Ray DM, Redonnet M, Phipps RP, Sime PJ. Burgess HA, et al. Among authors: ray dm. Am J Physiol Lung Cell Mol Physiol. 2005 Jun;288(6):L1146-53. doi: 10.1152/ajplung.00383.2004. Epub 2005 Feb 25. Am J Physiol Lung Cell Mol Physiol. 2005. PMID: 15734787 Free article.

6

CD40 engagement prevents peroxisome proliferator-activated receptor gamma agonist-induced apoptosis of B lymphocytes and B lymphoma cells by an NF-kappaB-dependent mechanism.

Ray DM, Akbiyik F, Bernstein SH, Phipps RP. Ray DM, et al. J Immunol. 2005 Apr 1;174(7):4060-9. doi: 10.4049/jimmunol.174.7.4060. J Immunol. 2005. PMID: 15778364

7

Platelets as a novel target for PPARgamma ligands : implications for inflammation, diabetes, and cardiovascular disease.

Ray DM, Spinelli SL, O'Brien JJ, Blumberg N, Phipps RP. Ray DM, et al. BioDrugs. 2006;20(4):231-41. doi: 10.2165/00063030-200620040-00004. BioDrugs. 2006. PMID: 16831022 Review.

8

More than structural cells, fibroblasts create and orchestrate the tumor microenvironment.

Baglole CJ, Ray DM, Bernstein SH, Feldon SE, Smith TJ, Sime PJ, Phipps RP. Baglole CJ, et al. Among authors: ray dm. Immunol Invest. 2006;35(3-4):297-325. doi: 10.1080/08820130600754960. Immunol Invest. 2006. PMID: 16916756 Review.

9

The novel triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO) induces apoptosis of human diffuse large B-cell lymphoma cells through a peroxisome proliferator-activated receptor gamma-independent pathway.

Ray DM, Morse KM, Hilchey SP, Garcia TM, Felgar RE, Maggirwar SB, Phipps RP, Bernstein SH. Ray DM, et al. Exp Hematol. 2006 Sep;34(9):1202-11. doi: 10.1016/j.exphem.2006.04.026. Exp Hematol. 2006. PMID: 16939813 Free article.

10

The platelet as a therapeutic target for treating vascular diseases and the role of eicosanoid and synthetic PPARgamma ligands.

O'Brien JJ, Ray DM, Spinelli SL, Blumberg N, Taubman MB, Francis CW, Wittlin SD, Phipps RP. O'Brien JJ, et al. Among authors: ray dm. Prostaglandins Other Lipid Mediat. 2007 Jan;82(1-4):68-76. doi: 10.1016/j.prostaglandins.2006.05.018. Epub 2006 Jul 10. Prostaglandins Other Lipid Mediat. 2007. PMID: 17164134 Review.

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