Crandall DL - Search Results

1

Effect of pharmacologic plasminogen activator inhibitor-1 inhibition on cell motility and tumor angiogenesis.

Leik CE, Su EJ, Nambi P, Crandall DL, Lawrence DA. Leik CE, et al. Among authors: crandall dl. J Thromb Haemost. 2006 Dec;4(12):2710-5. doi: 10.1111/j.1538-7836.2006.02244.x. Epub 2006 Oct 2. J Thromb Haemost. 2006. PMID: 17010152 Free article.

2

Pharmacologic inhibition of platelet vWF-GPIb alpha interaction prevents coronary artery thrombosis.

Hennan JK, Swillo RE, Morgan GA, Leik CE, Brooks JM, Shaw GD, Schaub RG, Crandall DL, Vlasuk GP. Hennan JK, et al. Among authors: crandall dl. Thromb Haemost. 2006 Mar;95(3):469-75. doi: 10.1160/TH05-09-0640. Thromb Haemost. 2006. PMID: 16525575

3

Modulation of adipose tissue development by pharmacological inhibition of PAI-1.

Crandall DL, Quinet EM, El Ayachi S, Hreha AL, Leik CE, Savio DA, Juhan-Vague I, Alessi MC. Crandall DL, et al. Arterioscler Thromb Vasc Biol. 2006 Oct;26(10):2209-15. doi: 10.1161/01.ATV.0000235605.51400.9d. Epub 2006 Jul 6. Arterioscler Thromb Vasc Biol. 2006. PMID: 16825598

4

Characterization and comparative evaluation of a structurally unique PAI-1 inhibitor exhibiting oral in-vivo efficacy.

Crandall DL, Elokdah H, Di L, Hennan JK, Gorlatova NV, Lawrence DA. Crandall DL, et al. J Thromb Haemost. 2004 Aug;2(8):1422-8. doi: 10.1111/j.1538-7836.2004.00829.x. J Thromb Haemost. 2004. PMID: 15304050 Free article.

5

Mechanism of inactivation of plasminogen activator inhibitor-1 by a small molecule inhibitor.

Gorlatova NV, Cale JM, Elokdah H, Li D, Fan K, Warnock M, Crandall DL, Lawrence DA. Gorlatova NV, et al. Among authors: crandall dl. J Biol Chem. 2007 Mar 23;282(12):9288-96. doi: 10.1074/jbc.M611642200. Epub 2007 Feb 2. J Biol Chem. 2007. PMID: 17276980 Free article.

6

GW3965, a synthetic liver X receptor (LXR) agonist, reduces angiotensin II-mediated pressor responses in Sprague-Dawley rats.

Leik CE, Carson NL, Hennan JK, Basso MD, Liu QY, Crandall DL, Nambi P. Leik CE, et al. Among authors: crandall dl. Br J Pharmacol. 2007 Jun;151(4):450-6. doi: 10.1038/sj.bjp.0707241. Epub 2007 Apr 10. Br J Pharmacol. 2007. PMID: 17420776 Free PMC article.

7

Effect of tiplaxtinin (PAI-039), an orally bioavailable PAI-1 antagonist, in a rat model of thrombosis.

Hennan JK, Morgan GA, Swillo RE, Antrilli TM, Mugford C, Vlasuk GP, Gardell SJ, Crandall DL. Hennan JK, et al. Among authors: crandall dl. J Thromb Haemost. 2008 Sep;6(9):1558-64. doi: 10.1111/j.1538-7836.2008.03063.x. Epub 2008 Jul 4. J Thromb Haemost. 2008. PMID: 18624980 Free article.

8

Mapping of a conformational epitope on plasminogen activator inhibitor-1 by random mutagenesis. Implications for serpin function.

Gorlatova NV, Elokdah H, Fan K, Crandall DL, Lawrence DA. Gorlatova NV, et al. Among authors: crandall dl. J Biol Chem. 2003 May 2;278(18):16329-35. doi: 10.1074/jbc.M208420200. Epub 2003 Feb 26. J Biol Chem. 2003. PMID: 12606560 Free article.

9

Synthesis and SAR of 2-carboxylic acid indoles as inhibitors of plasminogen activator inhibitor-1.

Hu B, Jetter JW, Wrobel JE, Antrilli TM, Bauer JS, Di L, Polakowski S, Jain U, Crandall DL. Hu B, et al. Among authors: crandall dl. Bioorg Med Chem Lett. 2005 Aug 1;15(15):3514-8. doi: 10.1016/j.bmcl.2005.05.095. Bioorg Med Chem Lett. 2005. PMID: 15982877

10

Neutralization of plasminogen activator inhibitor I (PAI-1) by the synthetic antagonist PAI-749 via a dual mechanism of action.

Gardell SJ, Krueger JA, Antrilli TA, Elokdah H, Mayer S, Orcutt SJ, Crandall DL, Vlasuk GP. Gardell SJ, et al. Among authors: crandall dl. Mol Pharmacol. 2007 Oct;72(4):897-906. doi: 10.1124/mol.107.037010. Epub 2007 Jul 10. Mol Pharmacol. 2007. PMID: 17622579

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