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Discovery of Pyrazolopyrazines as Selective, Potent, and Mutant-Active MET Inhibitors with Intracranial Efficacy.
Bumpers QA, Pipal RW, Benz-Weeden AM, Brewster JT 2nd, Cook A, Crooks AL, Cruz C, Dwulet NC, Gaudino JJ, Golec D, Harrison JA, Hartley DP, Hassanien SH, Hicken EJ, Kahn D, Laird ER, Lemieux C, Lewandowski N, McCown J, McDonald MG, McNulty O, Mou TC, Nguyen P, Oko L, Opie LP, Otten J, Peck SC, Polites VC, Randall SD, Rosen RZ, Savechenkov P, Simpson H, Singh A, Sparks D, Wickersham K, Wollenberg L, Wong CE, Wong J, Wu WI, Elsayed MSA, Hinklin RJ, Tang TP. Bumpers QA, et al. Among authors: harrison ja. J Med Chem. 2024 Aug 22;67(16):14466-14477. doi: 10.1021/acs.jmedchem.4c01232. Epub 2024 Aug 1. J Med Chem. 2024. PMID: 39088797
Stoichiometry and architecture of the human pyruvate dehydrogenase complex.
Zdanowicz R, Afanasyev P, Pruška A, Harrison JA, Giese C, Boehringer D, Leitner A, Zenobi R, Glockshuber R. Zdanowicz R, et al. Among authors: harrison ja. Sci Adv. 2024 Jul 19;10(29):eadn4582. doi: 10.1126/sciadv.adn4582. Epub 2024 Jul 17. Sci Adv. 2024. PMID: 39018392 Free PMC article.
Streamlining the Analysis of Proteins from Snake Venom.
Oganesyan I, Jenkins TP, Laustsen AH, Zenobi R, Harrison JA. Oganesyan I, et al. Among authors: harrison ja. J Proteome Res. 2024 Jul 5;23(7):2367-2375. doi: 10.1021/acs.jproteome.4c00013. Epub 2024 May 30. J Proteome Res. 2024. PMID: 38814071
183 results