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Stable tumor vessel normalization with pO₂ increase and endothelial PTEN activation by inositol trispyrophosphate brings novel tumor treatment.
Kieda C, El Hafny-Rahbi B, Collet G, Lamerant-Fayel N, Grillon C, Guichard A, Dulak J, Jozkowicz A, Kotlinowski J, Fylaktakidou KC, Vidal A, Auzeloux P, Miot-Noirault E, Beloeil JC, Lehn JM, Nicolau C. Kieda C, et al. Among authors: lehn jm. J Mol Med (Berl). 2013 Jul;91(7):883-99. doi: 10.1007/s00109-013-0992-6. Epub 2013 Mar 9. J Mol Med (Berl). 2013. PMID: 23471434 Free PMC article.
Enhanced exercise capacity in mice with severe heart failure treated with an allosteric effector of hemoglobin, myo-inositol trispyrophosphate.
Biolo A, Greferath R, Siwik DA, Qin F, Valsky E, Fylaktakidou KC, Pothukanuri S, Duarte CD, Schwarz RP, Lehn JM, Nicolau C, Colucci WS. Biolo A, et al. Among authors: lehn jm. Proc Natl Acad Sci U S A. 2009 Feb 10;106(6):1926-9. doi: 10.1073/pnas.0812381106. Epub 2009 Feb 9. Proc Natl Acad Sci U S A. 2009. PMID: 19204295 Free PMC article.
332 results