Zablocki J - Search Results

1

N6-Cycloalkyl-2-substituted adenosine derivatives as selective, high affinity adenosine A1 receptor agonists.

Elzein E, Kalla R, Li X, Perry T, Marquart T, Micklatcher M, Li Y, Wu Y, Zeng D, Zablocki J. Elzein E, et al. Among authors: zablocki j. Bioorg Med Chem Lett. 2007 Jan 1;17(1):161-6. doi: 10.1016/j.bmcl.2006.09.065. Epub 2006 Oct 11. Bioorg Med Chem Lett. 2007. PMID: 17045477

2

Novel inhibitors of fatty acid oxidation as potential metabolic modulators.

Elzein E, Shenk K, Ibrahim P, Marquart T, Kerwar S, Meyer S, Ahmed H, Zeng D, Chu N, Soohoo D, Wong S, Leung K, Zablocki J. Elzein E, et al. Among authors: zablocki j. Bioorg Med Chem Lett. 2004 Feb 23;14(4):973-7. doi: 10.1016/j.bmcl.2003.11.065. Bioorg Med Chem Lett. 2004. PMID: 15013004

3

2-Pyrazolyl-N(6)-substituted adenosine derivatives as high affinity and selective adenosine A(3) receptor agonists.

Elzein E, Palle V, Wu Y, Maa T, Zeng D, Zablocki J. Elzein E, et al. Among authors: zablocki j. J Med Chem. 2004 Sep 9;47(19):4766-73. doi: 10.1021/jm049682h. J Med Chem. 2004. PMID: 15341491

4

The discovery of a selective, high affinity A(2B) adenosine receptor antagonist for the potential treatment of asthma.

Zablocki J, Kalla R, Perry T, Palle V, Varkhedkar V, Xiao D, Piscopio A, Maa T, Gimbel A, Hao J, Chu N, Leung K, Zeng D. Zablocki J, et al. Bioorg Med Chem Lett. 2005 Feb 1;15(3):609-12. doi: 10.1016/j.bmcl.2004.11.044. Bioorg Med Chem Lett. 2005. PMID: 15664822

5

Novel 1,3-dipropyl-8-(1-heteroarylmethyl-1H-pyrazol-4-yl)-xanthine derivatives as high affinity and selective A2B adenosine receptor antagonists.

Elzein E, Kalla R, Li X, Perry T, Parkhill E, Palle V, Varkhedkar V, Gimbel A, Zeng D, Lustig D, Leung K, Zablocki J. Elzein E, et al. Among authors: zablocki j. Bioorg Med Chem Lett. 2006 Jan 15;16(2):302-6. doi: 10.1016/j.bmcl.2005.10.002. Epub 2005 Nov 4. Bioorg Med Chem Lett. 2006. PMID: 16275090

6

Novel 1,3-disubstituted 8-(1-benzyl-1H-pyrazol-4-yl) xanthines: high affinity and selective A2B adenosine receptor antagonists.

Kalla RV, Elzein E, Perry T, Li X, Palle V, Varkhedkar V, Gimbel A, Maa T, Zeng D, Zablocki J. Kalla RV, et al. Among authors: zablocki j. J Med Chem. 2006 Jun 15;49(12):3682-92. doi: 10.1021/jm051268+. J Med Chem. 2006. PMID: 16759111

7

Selective, high affinity A(2B) adenosine receptor antagonists: N-1 monosubstituted 8-(pyrazol-4-yl)xanthines.

Kalla RV, Elzein E, Perry T, Li X, Gimbel A, Yang M, Zeng D, Zablocki J. Kalla RV, et al. Among authors: zablocki j. Bioorg Med Chem Lett. 2008 Feb 15;18(4):1397-401. doi: 10.1016/j.bmcl.2008.01.008. Epub 2008 Jan 8. Bioorg Med Chem Lett. 2008. PMID: 18226896

8

Discovery of a novel A2B adenosine receptor antagonist as a clinical candidate for chronic inflammatory airway diseases.

Elzein E, Kalla RV, Li X, Perry T, Gimbel A, Zeng D, Lustig D, Leung K, Zablocki J. Elzein E, et al. Among authors: zablocki j. J Med Chem. 2008 Apr 10;51(7):2267-78. doi: 10.1021/jm7014815. Epub 2008 Mar 6. J Med Chem. 2008. PMID: 18321039

9

Progress in the discovery of selective, high affinity A(2B) adenosine receptor antagonists as clinical candidates.

Kalla RV, Zablocki J. Kalla RV, et al. Among authors: zablocki j. Purinergic Signal. 2009 Mar;5(1):21-9. doi: 10.1007/s11302-008-9119-x. Epub 2008 Jun 21. Purinergic Signal. 2009. PMID: 18568423 Free PMC article.

10

A1 adenosine receptor agonists and their potential therapeutic applications.

Elzein E, Zablocki J. Elzein E, et al. Among authors: zablocki j. Expert Opin Investig Drugs. 2008 Dec;17(12):1901-10. doi: 10.1517/13543780802497284. Expert Opin Investig Drugs. 2008. PMID: 19012505 Review.

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