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Powerful Avidity with a Limited Valency for Virus-Attachment Blockers on DC-SIGN: Combining Chelation and Statistical Rebinding with Structural Plasticity of the Receptor.
Porkolab V, Lepšík M, Ordanini S, St John A, Le Roy A, Thépaut M, Paci E, Ebel C, Bernardi A, Fieschi F. Porkolab V, et al. Among authors: fieschi f. ACS Cent Sci. 2023 Feb 20;9(4):709-718. doi: 10.1021/acscentsci.2c01136. eCollection 2023 Apr 26. ACS Cent Sci. 2023. PMID: 37122470 Free PMC article.
High-Mannose Oligosaccharide Hemimimetics that Recapitulate the Conformation and Binding Mode to Concanavalin A, DC-SIGN and Langerin.
Herrera-González I, González-Cuesta M, Thépaut M, Laigre E, Goyard D, Rojo J, García Fernández JM, Fieschi F, Renaudet O, Nieto PM, Ortiz Mellet C. Herrera-González I, et al. Among authors: fieschi f. Chemistry. 2024 Jan 8;30(2):e202303041. doi: 10.1002/chem.202303041. Epub 2023 Nov 14. Chemistry. 2024. PMID: 37828571
The unique 3D arrangement of macrophage galactose lectin enables Escherichia coli lipopolysaccharide recognition through two distinct interfaces.
Abbas M, Maalej M, Nieto-Fabregat F, Thépaut M, Kleman JP, Ayala I, Molinaro A, Simorre JP, Marchetti R, Fieschi F, Laguri C. Abbas M, et al. Among authors: fieschi f. PNAS Nexus. 2023 Sep 20;2(9):pgad310. doi: 10.1093/pnasnexus/pgad310. eCollection 2023 Sep. PNAS Nexus. 2023. PMID: 37780233 Free PMC article.
121 results