Distinct roles of catalytic and pexin-like domains in membrane-type matrix metalloproteinase (MMP)-mediated pro-MMP-2 activation and collagenolysis.
Jiang A, Pei D.
Jiang A, et al. Among authors: pei d.
J Biol Chem. 2003 Oct 3;278(40):38765-71. doi: 10.1074/jbc.M306618200. Epub 2003 Jul 23.
J Biol Chem. 2003.
PMID: 12878590
Free article.
Interestingly, the cytoplasmic domain of MT1-MMP behaves as a negative regulator not only for MT1-MMP itself, but also for MT3-MMP in both pro-MMP-2 activation and collagenolysis, consistent with and extending our recent findings (Jiang, A., Lehti, K., Wang, X., Weiss, S. J., Kes …
Interestingly, the cytoplasmic domain of MT1-MMP behaves as a negative regulator not only for MT1-MMP itself, but also for MT3-MMP in both p …