Targeted inhibition of sarcoplasmic reticulum CaMKII activity results in alterations of Ca2+ homeostasis and cardiac contractility.
Ji Y, Zhao W, Li B, Desantiago J, Picht E, Kaetzel MA, Schultz Jel J, Kranias EG, Bers DM, Dedman JR.
Ji Y, et al. Among authors: li b.
Am J Physiol Heart Circ Physiol. 2006 Feb;290(2):H599-606. doi: 10.1152/ajpheart.00214.2005. Epub 2005 Sep 2.
Am J Physiol Heart Circ Physiol. 2006.
PMID: 16143658
Free article.
Transgenic (TG) mice expressing a Ca2+/calmodulin-dependent protein kinase II (CaMKII) inhibitory peptide targeted to the cardiac myocyte longitudinal sarcoplasmic reticulum (LSR) display reduced phospholamban phosphorylation at Thr17 and develop dilated myopathy when stressed by …
Transgenic (TG) mice expressing a Ca2+/calmodulin-dependent protein kinase II (CaMKII) inhibitory peptide targeted to the cardiac myocyte lo …