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Chromosomal breakpoints affecting immunoglobulin loci are recurrent in Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma.
Martín-Subero JI, Klapper W, Sotnikova A, Callet-Bauchu E, Harder L, Bastard C, Schmitz R, Grohmann S, Höppner J, Riemke J, Barth TF, Berger F, Bernd HW, Claviez A, Gesk S, Frank GA, Kaplanskaya IB, Möller P, Parwaresch RM, Rüdiger T, Stein H, Küppers R, Hansmann ML, Siebert R; Deutsche Krebshilfe Network Project Molecular Mechanisms in Malignant Lymphomas. Martín-Subero JI, et al. Among authors: siebert r. Cancer Res. 2006 Nov 1;66(21):10332-8. doi: 10.1158/0008-5472.CAN-06-1992. Cancer Res. 2006. PMID: 17079453
Molecular analysis of single B cells from T-cell-rich B-cell lymphoma shows the derivation of the tumor cells from mutating germinal center B cells and exemplifies means by which immunoglobulin genes are modified in germinal center B cells.
Bräuninger A, Küppers R, Spieker T, Siebert R, Strickler JG, Schlegelberger B, Rajewsky K, Hansmann ML. Bräuninger A, et al. Among authors: siebert r. Blood. 1999 Apr 15;93(8):2679-87. Blood. 1999. PMID: 10194448 Free article.
766 results