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Lymphopenia in the BB rat model of type 1 diabetes is due to a mutation in a novel immune-associated nucleotide (Ian)-related gene.
MacMurray AJ, Moralejo DH, Kwitek AE, Rutledge EA, Van Yserloo B, Gohlke P, Speros SJ, Snyder B, Schaefer J, Bieg S, Jiang J, Ettinger RA, Fuller J, Daniels TL, Pettersson A, Orlebeke K, Birren B, Jacob HJ, Lander ES, Lernmark A. MacMurray AJ, et al. Among authors: lernmark a. Genome Res. 2002 Jul;12(7):1029-39. doi: 10.1101/gr.412702. Genome Res. 2002. PMID: 12097339 Free PMC article.
Transgenic rescue demonstrates involvement of the Ian5 gene in T cell development in the rat.
Michalkiewicz M, Michalkiewicz T, Ettinger RA, Rutledge EA, Fuller JM, Moralejo DH, Van Yserloo B, MacMurray AJ, Kwitek AE, Jacob HJ, Lander ES, Lernmark A. Michalkiewicz M, et al. Among authors: lernmark a. Physiol Genomics. 2004 Oct 4;19(2):228-32. doi: 10.1152/physiolgenomics.00126.2004. Epub 2004 Aug 24. Physiol Genomics. 2004. PMID: 15328390
Impaired survival of peripheral T cells, disrupted NK/NKT cell development, and liver failure in mice lacking Gimap5.
Schulteis RD, Chu H, Dai X, Chen Y, Edwards B, Haribhai D, Williams CB, Malarkannan S, Hessner MJ, Glisic-Milosavljevic S, Jana S, Kerschen EJ, Ghosh S, Wang D, Kwitek AE, Lernmark A, Gorski J, Weiler H. Schulteis RD, et al. Among authors: lernmark a. Blood. 2008 Dec 15;112(13):4905-14. doi: 10.1182/blood-2008-03-146555. Epub 2008 Sep 16. Blood. 2008. PMID: 18796632 Free PMC article.
Sequence variation and expression of the Gimap gene family in the BB rat.
Rutledge EA, Fuller JM, Van Yserloo B, Moralejo DH, Ettinger RA, Gaur P, Hoehna JL, Peterson MR, Jensen R, Kwitek AE, Lernmark A. Rutledge EA, et al. Among authors: lernmark a. Exp Diabetes Res. 2009;2009:835650. doi: 10.1155/2009/835650. Epub 2009 May 3. Exp Diabetes Res. 2009. PMID: 19421422 Free PMC article.
BB rat Gimap gene expression in sorted lymphoid T and B cells.
Moralejo DH, Fuller JM, Rutledge EA, Van Yserloo B, Ettinger RA, Jensen R, Osborne W, Kwitek A, Lernmark A. Moralejo DH, et al. Among authors: lernmark a. Life Sci. 2011 Nov 7;89(19-20):748-54. doi: 10.1016/j.lfs.2011.08.016. Epub 2011 Sep 10. Life Sci. 2011. PMID: 21925515 Free PMC article.
783 results