Reff M - Search Results

1

Enhanced cell culture performance using inducible anti-apoptotic genes E1B-19K and Aven in the production of a monoclonal antibody with Chinese hamster ovary cells.

Figueroa B Jr, Ailor E, Osborne D, Hardwick JM, Reff M, Betenbaugh MJ. Figueroa B Jr, et al. Among authors: reff m. Biotechnol Bioeng. 2007 Jul 1;97(4):877-92. doi: 10.1002/bit.21222. Biotechnol Bioeng. 2007. PMID: 17099908

2

Expression of GnTIII in a recombinant anti-CD20 CHO production cell line: Expression of antibodies with altered glycoforms leads to an increase in ADCC through higher affinity for FC gamma RIII.

Davies J, Jiang L, Pan LZ, LaBarre MJ, Anderson D, Reff M. Davies J, et al. Among authors: reff m. Biotechnol Bioeng. 2001 Aug 20;74(4):288-94. Biotechnol Bioeng. 2001. PMID: 11410853

3

Characterization of inhibitory anti-insulin-like growth factor receptor antibodies with different epitope specificity and ligand-blocking properties: implications for mechanism of action in vivo.

Doern A, Cao X, Sereno A, Reyes CL, Altshuler A, Huang F, Hession C, Flavier A, Favis M, Tran H, Ailor E, Levesque M, Murphy T, Berquist L, Tamraz S, Snipas T, Garber E, Shestowsky WS, Rennard R, Graff CP, Wu X, Snyder W, Cole L, Gregson D, Shields M, Ho SN, Reff ME, Glaser SM, Dong J, Demarest SJ, Hariharan K. Doern A, et al. Among authors: reff me. J Biol Chem. 2009 Apr 10;284(15):10254-67. doi: 10.1074/jbc.M809709200. Epub 2009 Feb 11. J Biol Chem. 2009. PMID: 19211557 Free PMC article.

4

Chromosome localization and gene-copy-number quantification of three random integrations in Chinese-hamster ovary cells and their amplified cell lines using fluorescence in situ hybridization.

Davies J, Reff M. Davies J, et al. Among authors: reff m. Biotechnol Appl Biochem. 2001 Apr;33(2):99-105. doi: 10.1042/ba20000090. Biotechnol Appl Biochem. 2001. PMID: 11277862

5

Depletion of B cells in vivo by a chimeric mouse human monoclonal antibody to CD20.

Reff ME, Carner K, Chambers KS, Chinn PC, Leonard JE, Raab R, Newman RA, Hanna N, Anderson DR. Reff ME, et al. Blood. 1994 Jan 15;83(2):435-45. Blood. 1994. PMID: 7506951 Free article.

6

In vitro IgE inhibition in B cells by anti-CD23 monoclonal antibodies is functionally dependent on the immunoglobulin Fc domain.

Nakamura T, Kloetzer WS, Brams P, Hariharan K, Chamat S, Cao X, LaBarre MJ, Chinn PC, Morena RA, Shestowsky WS, Li YP, Chen A, Reff ME. Nakamura T, et al. Among authors: reff me. Int J Immunopharmacol. 2000 Feb;22(2):131-41. doi: 10.1016/s0192-0561(99)00068-5. Int J Immunopharmacol. 2000. PMID: 10684997

7

"Primatization" of recombinant antibodies for immunotherapy of human diseases: a macaque/human chimeric antibody against human CD4.

Newman R, Alberts J, Anderson D, Carner K, Heard C, Norton F, Raab R, Reff M, Shuey S, Hanna N. Newman R, et al. Among authors: reff m. Biotechnology (N Y). 1992 Nov;10(11):1455-60. doi: 10.1038/nbt1192-1455. Biotechnology (N Y). 1992. PMID: 1369023

8

A primatized MAb to human CD4 causes receptor modulation, without marked reduction in CD4+ T cells in chimpanzees: in vitro and in vivo characterization of a MAb (IDEC-CE9.1) to human CD4.

Anderson D, Chambers K, Hanna N, Leonard J, Reff M, Newman R, Baldoni J, Dunleavy D, Reddy M, Sweet R, Truneh A. Anderson D, et al. Among authors: reff m. Clin Immunol Immunopathol. 1997 Jul;84(1):73-84. doi: 10.1006/clin.1997.4363. Clin Immunol Immunopathol. 1997. PMID: 9191886

9

Modification of the Fc region of a primatized IgG antibody to human CD4 retains its ability to modulate CD4 receptors but does not deplete CD4(+) T cells in chimpanzees.

Newman R, Hariharan K, Reff M, Anderson DR, Braslawsky G, Santoro D, Hanna N, Bugelski PJ, Brigham-Burke M, Crysler C, Gagnon RC, Dal Monte P, Doyle ML, Hensley PC, Reddy MP, Sweet RW, Truneh A. Newman R, et al. Among authors: reff m. Clin Immunol. 2001 Feb;98(2):164-74. doi: 10.1006/clim.2000.4975. Clin Immunol. 2001. PMID: 11161972

10

Elimination of Fc receptor-dependent effector functions of a modified IgG4 monoclonal antibody to human CD4.

Reddy MP, Kinney CA, Chaikin MA, Payne A, Fishman-Lobell J, Tsui P, Dal Monte PR, Doyle ML, Brigham-Burke MR, Anderson D, Reff M, Newman R, Hanna N, Sweet RW, Truneh A. Reddy MP, et al. Among authors: reff m. J Immunol. 2000 Feb 15;164(4):1925-33. doi: 10.4049/jimmunol.164.4.1925. J Immunol. 2000. PMID: 10657642

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