Filpula D - Search Results

1

Engineering an arginine catabolizing bioconjugate: Biochemical and pharmacological characterization of PEGylated derivatives of arginine deiminase from Mycoplasma arthritidis.

Wang M, Basu A, Palm T, Hua J, Youngster S, Hwang L, Liu HC, Li X, Peng P, Zhang Y, Zhao H, Zhang Z, Longley C, Mehlig M, Borowski V, Sai P, Viswanathan M, Jang E, Petti G, Liu S, Yang K, Filpula D. Wang M, et al. Among authors: filpula d. Bioconjug Chem. 2006 Nov-Dec;17(6):1447-59. doi: 10.1021/bc060198y. Bioconjug Chem. 2006. PMID: 17105223

2

Linear and branched bicin linkers for releasable PEGylation of macromolecules: controlled release in vivo and in vitro from mono- and multi-PEGylated proteins.

Zhao H, Yang K, Martinez A, Basu A, Chintala R, Liu HC, Janjua A, Wang M, Filpula D. Zhao H, et al. Among authors: filpula d. Bioconjug Chem. 2006 Mar-Apr;17(2):341-51. doi: 10.1021/bc050270c. Bioconjug Chem. 2006. PMID: 16536464

3

Structure-function engineering of interferon-beta-1b for improving stability, solubility, potency, immunogenicity, and pharmacokinetic properties by site-selective mono-PEGylation.

Basu A, Yang K, Wang M, Liu S, Chintala R, Palm T, Zhao H, Peng P, Wu D, Zhang Z, Hua J, Hsieh MC, Zhou J, Petti G, Li X, Janjua A, Mendez M, Liu J, Longley C, Zhang Z, Mehlig M, Borowski V, Viswanathan M, Filpula D. Basu A, et al. Among authors: filpula d. Bioconjug Chem. 2006 May-Jun;17(3):618-30. doi: 10.1021/bc050322y. Bioconjug Chem. 2006. PMID: 16704199

4

Releasable PEGylation of mesothelin targeted immunotoxin SS1P achieves single dosage complete regression of a human carcinoma in mice.

Filpula D, Yang K, Basu A, Hassan R, Xiang L, Zhang Z, Wang M, Wang QC, Ho M, Beers R, Zhao H, Peng P, Zhou J, Li X, Petti G, Janjua A, Liu J, Wu D, Yu D, Zhang Z, Longley C, FitzGerald D, Kreitman RJ, Pastan I. Filpula D, et al. Bioconjug Chem. 2007 May-Jun;18(3):773-84. doi: 10.1021/bc060314x. Epub 2007 Mar 9. Bioconjug Chem. 2007. PMID: 17346030

5

Controlled release of proteins from their poly(ethylene glycol) conjugates: drug delivery systems employing 1,6-elimination.

Greenwald RB, Yang K, Zhao H, Conover CD, Lee S, Filpula D. Greenwald RB, et al. Among authors: filpula d. Bioconjug Chem. 2003 Mar-Apr;14(2):395-403. doi: 10.1021/bc025652m. Bioconjug Chem. 2003. PMID: 12643750

6

Tailoring structure-function and pharmacokinetic properties of single-chain Fv proteins by site-specific PEGylation.

Yang K, Basu A, Wang M, Chintala R, Hsieh MC, Liu S, Hua J, Zhang Z, Zhou J, Li M, Phyu H, Petti G, Mendez M, Janjua H, Peng P, Longley C, Borowski V, Mehlig M, Filpula D. Yang K, et al. Among authors: filpula d. Protein Eng. 2003 Oct;16(10):761-70. doi: 10.1093/protein/gzg093. Protein Eng. 2003. PMID: 14600206

7

Antitumor activity of poly(ethylene glycol)-camptothecin conjugate: the inhibition of tumor growth in vivo.

Yu D, Peng P, Dharap SS, Wang Y, Mehlig M, Chandna P, Zhao H, Filpula D, Yang K, Borowski V, Borchard G, Zhang Z, Minko T. Yu D, et al. Among authors: filpula d. J Control Release. 2005 Dec 10;110(1):90-102. doi: 10.1016/j.jconrel.2005.09.050. Epub 2005 Nov 4. J Control Release. 2005. PMID: 16271793

8

Releasable PEGylation of proteins with customized linkers.

Filpula D, Zhao H. Filpula D, et al. Adv Drug Deliv Rev. 2008 Jan 3;60(1):29-49. doi: 10.1016/j.addr.2007.02.001. Epub 2007 Aug 16. Adv Drug Deliv Rev. 2008. PMID: 17884239 Review.

9

Prolonged circulating lives of single-chain Fv proteins conjugated with polyethylene glycol: a comparison of conjugation chemistries and compounds.

Lee LS, Conover C, Shi C, Whitlow M, Filpula D. Lee LS, et al. Among authors: filpula d. Bioconjug Chem. 1999 Nov-Dec;10(6):973-81. doi: 10.1021/bc990076o. Bioconjug Chem. 1999. PMID: 10563766

10

Antibody engineering and modification technologies.

Filpula D. Filpula D. Biomol Eng. 2007 Jun;24(2):201-15. doi: 10.1016/j.bioeng.2007.03.004. Epub 2007 Mar 31. Biomol Eng. 2007. PMID: 17466589 Review.

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