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Safety and efficacy of memantine and trazodone versus placebo for motor neuron disease (MND SMART): stage two interim analysis from the first cycle of a phase 3, multiarm, multistage, randomised, adaptive platform trial.
Pal S, Chataway J, Swingler R, Macleod MR, Carragher NO, Hardingham G, Selvaraj BT, Smith C, Wong C, Newton J, Lyle D, Stenson A, Dakin RS, Ihenacho A, Colville S, Mehta AR, Stallard N, Carpenter JR, Parker RA, Keerie C, Weir CJ, Virgo B, Morris S, Waters N, Gray B, MacDonald D, MacDonald E, Parmar MKB, Chandran S; MND SMART Investigators. Pal S, et al. Among authors: dakin rs. Lancet Neurol. 2024 Nov;23(11):1097-1107. doi: 10.1016/S1474-4422(24)00326-0. Epub 2024 Sep 19. Lancet Neurol. 2024. PMID: 39307154 Free article. Clinical Trial.
Non-motor symptoms in motor neuron disease: prevalence, assessment and impact.
Beswick E, Forbes D, Johnson M, Newton J, Dakin R, Glasmcher S, Abrahams S, Carson A, Chandran S, Pal S. Beswick E, et al. Among authors: dakin r. Brain Commun. 2023 Dec 7;6(1):fcad336. doi: 10.1093/braincomms/fcad336. eCollection 2024. Brain Commun. 2023. PMID: 38162906 Free PMC article.
Factors impacting trial participation in people with motor neuron disease.
Beswick E, Johnson M, Newton J, Dakin R, Stenson A, Abrahams S, Carson A, Chandran S, Pal S. Beswick E, et al. Among authors: dakin r. J Neurol. 2024 Jan;271(1):543-552. doi: 10.1007/s00415-023-12010-8. Epub 2023 Oct 3. J Neurol. 2024. PMID: 37787812 Free PMC article. Clinical Trial.
56 results