Mirzadegan T - Search Results

1

Substrate-dependent inhibition or stimulation of HIV RNase H activity by non-nucleoside reverse transcriptase inhibitors (NNRTIs).

Hang JQ, Li Y, Yang Y, Cammack N, Mirzadegan T, Klumpp K. Hang JQ, et al. Among authors: mirzadegan t. Biochem Biophys Res Commun. 2007 Jan 12;352(2):341-50. doi: 10.1016/j.bbrc.2006.11.018. Epub 2006 Nov 14. Biochem Biophys Res Commun. 2007. PMID: 17113568

2

Recent progress in the design of small molecule inhibitors of HIV RNase H.

Klumpp K, Mirzadegan T. Klumpp K, et al. Among authors: mirzadegan t. Curr Pharm Des. 2006;12(15):1909-22. doi: 10.2174/138161206776873653. Curr Pharm Des. 2006. PMID: 16724956 Review.

3

Highly potent, non-basic 5-HT6 ligands. Site mutagenesis evidence for a second binding mode at 5-HT6 for antagonism.

Harris RN 3rd, Stabler RS, Repke DB, Kress JM, Walker KA, Martin RS, Brothers JM, Ilnicka M, Lee SW, Mirzadegan T. Harris RN 3rd, et al. Among authors: mirzadegan t. Bioorg Med Chem Lett. 2010 Jun 1;20(11):3436-40. doi: 10.1016/j.bmcl.2010.03.110. Epub 2010 Apr 1. Bioorg Med Chem Lett. 2010. PMID: 20434910

4

Molecular interactions of CCR5 with major classes of small-molecule anti-HIV CCR5 antagonists.

Kondru R, Zhang J, Ji C, Mirzadegan T, Rotstein D, Sankuratri S, Dioszegi M. Kondru R, et al. Among authors: mirzadegan t. Mol Pharmacol. 2008 Mar;73(3):789-800. doi: 10.1124/mol.107.042101. Epub 2007 Dec 20. Mol Pharmacol. 2008. PMID: 18096812

5

Rational design of 6-methylsulfonylindoles as selective cyclooxygenase-2 inhibitors.

Campbell JA, Bordunov V, Broka CA, Browner MF, Kress JM, Mirzadegan T, Ramesha C, Sanpablo BF, Stabler R, Takahara P, Villasenor A, Walker KA, Wang JH, Welch M, Weller P. Campbell JA, et al. Among authors: mirzadegan t. Bioorg Med Chem Lett. 2004 Sep 20;14(18):4741-5. doi: 10.1016/j.bmcl.2004.06.075. Bioorg Med Chem Lett. 2004. PMID: 15324899

6

Identification of the binding site for a novel class of CCR2b chemokine receptor antagonists: binding to a common chemokine receptor motif within the helical bundle.

Mirzadegan T, Diehl F, Ebi B, Bhakta S, Polsky I, McCarley D, Mulkins M, Weatherhead GS, Lapierre JM, Dankwardt J, Morgans D Jr, Wilhelm R, Jarnagin K. Mirzadegan T, et al. J Biol Chem. 2000 Aug 18;275(33):25562-71. doi: 10.1074/jbc.M000692200. J Biol Chem. 2000. PMID: 10770925 Free article.

7

Lactams as EP4 prostanoid receptor agonists. 3. Discovery of N-ethylbenzoic acid 2-pyrrolidinones as subtype selective agents.

Elworthy TR, Brill ER, Chiou SS, Chu F, Harris JR, Hendricks RT, Huang J, Kim W, Lach LK, Mirzadegan T, Yee C, Walker KA. Elworthy TR, et al. Among authors: mirzadegan t. J Med Chem. 2004 Dec 2;47(25):6124-7. doi: 10.1021/jm049290a. J Med Chem. 2004. PMID: 15566283

8

Pharmacological characterization of 1-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid (JNJ-42041935), a potent and selective hypoxia-inducible factor prolyl hydroxylase inhibitor.

Barrett TD, Palomino HL, Brondstetter TI, Kanelakis KC, Wu X, Haug PV, Yan W, Young A, Hua H, Hart JC, Tran DT, Venkatesan H, Rosen MD, Peltier HM, Sepassi K, Rizzolio MC, Bembenek SD, Mirzadegan T, Rabinowitz MH, Shankley NP. Barrett TD, et al. Among authors: mirzadegan t. Mol Pharmacol. 2011 Jun;79(6):910-20. doi: 10.1124/mol.110.070508. Epub 2011 Mar 3. Mol Pharmacol. 2011. PMID: 21372172

9

Analysis of the structural and molecular basis of voltage-sensitive sodium channel inhibition by the spider toxin huwentoxin-IV (μ-TRTX-Hh2a).

Minassian NA, Gibbs A, Shih AY, Liu Y, Neff RA, Sutton SW, Mirzadegan T, Connor J, Fellows R, Husovsky M, Nelson S, Hunter MJ, Flinspach M, Wickenden AD. Minassian NA, et al. Among authors: mirzadegan t. J Biol Chem. 2013 Aug 2;288(31):22707-20. doi: 10.1074/jbc.M113.461392. Epub 2013 Jun 12. J Biol Chem. 2013. PMID: 23760503 Free PMC article.

10

Identification of residues in the monocyte chemotactic protein-1 that contact the MCP-1 receptor, CCR2.

Hemmerich S, Paavola C, Bloom A, Bhakta S, Freedman R, Grunberger D, Krstenansky J, Lee S, McCarley D, Mulkins M, Wong B, Pease J, Mizoue L, Mirzadegan T, Polsky I, Thompson K, Handel TM, Jarnagin K. Hemmerich S, et al. Among authors: mirzadegan t. Biochemistry. 1999 Oct 5;38(40):13013-25. doi: 10.1021/bi991029m. Biochemistry. 1999. PMID: 10529171

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