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Page 1
A fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo.
Verdoes M, Florea BI, Menendez-Benito V, Maynard CJ, Witte MD, van der Linden WA, van den Nieuwendijk AM, Hofmann T, Berkers CR, van Leeuwen FW, Groothuis TA, Leeuwenburgh MA, Ovaa H, Neefjes JJ, Filippov DV, van der Marel GA, Dantuma NP, Overkleeft HS. Verdoes M, et al. Among authors: van der marel ga, van der linden wa, van den nieuwendijk am, van leeuwen fw. Chem Biol. 2006 Nov;13(11):1217-26. doi: 10.1016/j.chembiol.2006.09.013. Chem Biol. 2006. PMID: 17114003
Chemistry in living cells: detection of active proteasomes by a two-step labeling strategy.
Ovaa H, van Swieten PF, Kessler BM, Leeuwenburgh MA, Fiebiger E, van den Nieuwendijk AM, Galardy PJ, van der Marel GA, Ploegh HL, Overkleeft HS. Ovaa H, et al. Among authors: van der marel ga, van den nieuwendijk am, van swieten pf. Angew Chem Int Ed Engl. 2003 Aug 11;42(31):3626-9. doi: 10.1002/anie.200351314. Angew Chem Int Ed Engl. 2003. PMID: 12916032 No abstract available.
Development of an isotope-coded activity-based probe for the quantitative profiling of cysteine proteases.
van Swieten PF, Maehr R, van den Nieuwendijk AM, Kessler BM, Reich M, Wong CS, Kalbacher H, Leeuwenburgh MA, Driessen C, van der Marel GA, Ploegh HL, Overkleeft HS. van Swieten PF, et al. Among authors: van der marel ga, van den nieuwendijk am. Bioorg Med Chem Lett. 2004 Jun 21;14(12):3131-4. doi: 10.1016/j.bmcl.2004.04.046. Bioorg Med Chem Lett. 2004. PMID: 15149659
A cell-permeable inhibitor and activity-based probe for the caspase-like activity of the proteasome.
van Swieten PF, Samuel E, Hernández RO, van den Nieuwendijk AM, Leeuwenburgh MA, van der Marel GA, Kessler BM, Overkleeft HS, Kisselev AF. van Swieten PF, et al. Among authors: van der marel ga, van den nieuwendijk am. Bioorg Med Chem Lett. 2007 Jun 15;17(12):3402-5. doi: 10.1016/j.bmcl.2007.03.092. Epub 2007 Apr 2. Bioorg Med Chem Lett. 2007. PMID: 17442566
Ultrasensitive in situ visualization of active glucocerebrosidase molecules.
Witte MD, Kallemeijn WW, Aten J, Li KY, Strijland A, Donker-Koopman WE, van den Nieuwendijk AM, Bleijlevens B, Kramer G, Florea BI, Hooibrink B, Hollak CE, Ottenhoff R, Boot RG, van der Marel GA, Overkleeft HS, Aerts JM. Witte MD, et al. Among authors: van der marel ga, van den nieuwendijk am. Nat Chem Biol. 2010 Dec;6(12):907-13. doi: 10.1038/nchembio.466. Epub 2010 Oct 31. Nat Chem Biol. 2010. PMID: 21079602 Free article.
Identification and development of biphenyl substituted iminosugars as improved dual glucosylceramide synthase/neutral glucosylceramidase inhibitors.
Ghisaidoobe AT, van den Berg RJ, Butt SS, Strijland A, Donker-Koopman WE, Scheij S, van den Nieuwendijk AM, Koomen GJ, van Loevezijn A, Leemhuis M, Wennekes T, van der Stelt M, van der Marel GA, van Boeckel CA, Aerts JM, Overkleeft HS. Ghisaidoobe AT, et al. Among authors: van der stelt m, van loevezijn a, van der marel ga, van boeckel ca, van den nieuwendijk am, van den berg rj. J Med Chem. 2014 Nov 13;57(21):9096-104. doi: 10.1021/jm501181z. Epub 2014 Oct 17. J Med Chem. 2014. PMID: 25250725
Synthesis of 6-Hydroxysphingosine and α-Hydroxy Ceramide Using a Cross-Metathesis Strategy.
Wisse P, de Geus MA, Cross G, van den Nieuwendijk AM, van Rooden EJ, van den Berg RJ, Aerts JM, van der Marel GA, Codée JD, Overkleeft HS. Wisse P, et al. Among authors: van rooden ej, van der marel ga, van den nieuwendijk am, van den berg rj. J Org Chem. 2015 Jul 17;80(14):7258-65. doi: 10.1021/acs.joc.5b00823. Epub 2015 Jun 25. J Org Chem. 2015. PMID: 26061009
30 results