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Page 1
1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazoles: identification of a potent Aurora kinase inhibitor with a favorable antitumor kinase inhibition profile.
Fancelli D, Moll J, Varasi M, Bravo R, Artico R, Berta D, Bindi S, Cameron A, Candiani I, Cappella P, Carpinelli P, Croci W, Forte B, Giorgini ML, Klapwijk J, Marsiglio A, Pesenti E, Rocchetti M, Roletto F, Severino D, Soncini C, Storici P, Tonani R, Zugnoni P, Vianello P. Fancelli D, et al. Among authors: zugnoni p. J Med Chem. 2006 Nov 30;49(24):7247-51. doi: 10.1021/jm060897w. J Med Chem. 2006. PMID: 17125279
PHA-680632, a novel Aurora kinase inhibitor with potent antitumoral activity.
Soncini C, Carpinelli P, Gianellini L, Fancelli D, Vianello P, Rusconi L, Storici P, Zugnoni P, Pesenti E, Croci V, Ceruti R, Giorgini ML, Cappella P, Ballinari D, Sola F, Varasi M, Bravo R, Moll J. Soncini C, et al. Among authors: zugnoni p. Clin Cancer Res. 2006 Jul 1;12(13):4080-9. doi: 10.1158/1078-0432.CCR-05-1964. Clin Cancer Res. 2006. PMID: 16818708
PHA-739358, a potent inhibitor of Aurora kinases with a selective target inhibition profile relevant to cancer.
Carpinelli P, Ceruti R, Giorgini ML, Cappella P, Gianellini L, Croci V, Degrassi A, Texido G, Rocchetti M, Vianello P, Rusconi L, Storici P, Zugnoni P, Arrigoni C, Soncini C, Alli C, Patton V, Marsiglio A, Ballinari D, Pesenti E, Fancelli D, Moll J. Carpinelli P, et al. Among authors: zugnoni p. Mol Cancer Ther. 2007 Dec;6(12 Pt 1):3158-68. doi: 10.1158/1535-7163.MCT-07-0444. Mol Cancer Ther. 2007. PMID: 18089710
Thieno[3,2-c]pyrazoles: a novel class of Aurora inhibitors with favorable antitumor activity.
Bindi S, Fancelli D, Alli C, Berta D, Bertrand JA, Cameron AD, Cappella P, Carpinelli P, Cervi G, Croci V, D'Anello M, Forte B, Giorgini ML, Marsiglio A, Moll J, Pesenti E, Pittalà V, Pulici M, Riccardi-Sirtori F, Roletto F, Soncini C, Storici P, Varasi M, Volpi D, Zugnoni P, Vianello P. Bindi S, et al. Among authors: zugnoni p. Bioorg Med Chem. 2010 Oct 1;18(19):7113-20. doi: 10.1016/j.bmc.2010.07.048. Epub 2010 Jul 25. Bioorg Med Chem. 2010. PMID: 20817473
A pharmacokinetic-pharmacodynamic model for predicting tumour growth inhibition in mice: a useful tool in oncology drug development.
Rocchetti M, Poggesi I, Germani M, Fiorentini F, Pellizzoni C, Zugnoni P, Pesenti E, Simeoni M, De Nicolao G. Rocchetti M, et al. Among authors: zugnoni p. Basic Clin Pharmacol Toxicol. 2005 Mar;96(3):265-8. doi: 10.1111/j.1742-7843.2005.pto960325.x. Basic Clin Pharmacol Toxicol. 2005. PMID: 15733231 Free article. No abstract available.