Dougall WC - Search Results

1

RANK overexpression in transgenic mice with mouse mammary tumor virus promoter-controlled RANK increases proliferation and impairs alveolar differentiation in the mammary epithelia and disrupts lumen formation in cultured epithelial acini.

Gonzalez-Suarez E, Branstetter D, Armstrong A, Dinh H, Blumberg H, Dougall WC. Gonzalez-Suarez E, et al. Among authors: dougall wc. Mol Cell Biol. 2007 Feb;27(4):1442-54. doi: 10.1128/MCB.01298-06. Epub 2006 Dec 4. Mol Cell Biol. 2007. PMID: 17145767 Free PMC article.

2

RANK is essential for osteoclast and lymph node development.

Dougall WC, Glaccum M, Charrier K, Rohrbach K, Brasel K, De Smedt T, Daro E, Smith J, Tometsko ME, Maliszewski CR, Armstrong A, Shen V, Bain S, Cosman D, Anderson D, Morrissey PJ, Peschon JJ, Schuh J. Dougall WC, et al. Genes Dev. 1999 Sep 15;13(18):2412-24. doi: 10.1101/gad.13.18.2412. Genes Dev. 1999. PMID: 10500098 Free PMC article.

3

A RANK/TRAF6-dependent signal transduction pathway is essential for osteoclast cytoskeletal organization and resorptive function.

Armstrong AP, Tometsko ME, Glaccum M, Sutherland CL, Cosman D, Dougall WC. Armstrong AP, et al. Among authors: dougall wc. J Biol Chem. 2002 Nov 15;277(46):44347-56. doi: 10.1074/jbc.M202009200. Epub 2002 Aug 15. J Biol Chem. 2002. PMID: 12185073 Free article.

4

Osteoclast differentiation is impaired in the absence of inhibitor of kappa B kinase alpha.

Chaisson ML, Branstetter DG, Derry JM, Armstrong AP, Tometsko ME, Takeda K, Akira S, Dougall WC. Chaisson ML, et al. Among authors: dougall wc. J Biol Chem. 2004 Dec 24;279(52):54841-8. doi: 10.1074/jbc.M406392200. Epub 2004 Oct 14. J Biol Chem. 2004. PMID: 15485831 Free article.

5

The RANK/RANKL/OPG triad in cancer-induced bone diseases.

Dougall WC, Chaisson M. Dougall WC, et al. Cancer Metastasis Rev. 2006 Dec;25(4):541-9. doi: 10.1007/s10555-006-9021-3. Cancer Metastasis Rev. 2006. PMID: 17180711 Review.

6

Detection of myeloma in skeleton of mice by whole-body optical fluorescence imaging.

Oyajobi BO, Muñoz S, Kakonen R, Williams PJ, Gupta A, Wideman CL, Story B, Grubbs B, Armstrong A, Dougall WC, Garrett IR, Mundy GR. Oyajobi BO, et al. Among authors: dougall wc. Mol Cancer Ther. 2007 Jun;6(6):1701-8. doi: 10.1158/1535-7163.MCT-07-0121. Epub 2007 May 31. Mol Cancer Ther. 2007. PMID: 17541032 Free PMC article.

7

Receptor activator of NF-kappa B ligand inhibition suppresses bone resorption and hypercalcemia but does not affect host immune responses to influenza infection.

Miller RE, Branstetter D, Armstrong A, Kennedy B, Jones J, Cowan L, Bussiere J, Dougall WC. Miller RE, et al. Among authors: dougall wc. J Immunol. 2007 Jul 1;179(1):266-74. doi: 10.4049/jimmunol.179.1.266. J Immunol. 2007. PMID: 17579046

8

RANKL acts directly on RANK-expressing prostate tumor cells and mediates migration and expression of tumor metastasis genes.

Armstrong AP, Miller RE, Jones JC, Zhang J, Keller ET, Dougall WC. Armstrong AP, et al. Among authors: dougall wc. Prostate. 2008 Jan 1;68(1):92-104. doi: 10.1002/pros.20678. Prostate. 2008. PMID: 18008334 Free article.

9

RANK ligand inhibition plus docetaxel improves survival and reduces tumor burden in a murine model of prostate cancer bone metastasis.

Miller RE, Roudier M, Jones J, Armstrong A, Canon J, Dougall WC. Miller RE, et al. Among authors: dougall wc. Mol Cancer Ther. 2008 Jul;7(7):2160-9. doi: 10.1158/1535-7163.MCT-08-0046. Epub 2008 Jul 7. Mol Cancer Ther. 2008. PMID: 18606716

10

Combined therapy with the RANKL inhibitor RANK-Fc and rhApo2L/TRAIL/dulanermin reduces bone lesions and skeletal tumor burden in a model of breast cancer skeletal metastasis.

Holland PM, Miller R, Jones J, Douangpanya H, Piasecki J, Roudier M, Dougall WC. Holland PM, et al. Among authors: dougall wc. Cancer Biol Ther. 2010 Apr 1;9(7):539-50. doi: 10.4161/cbt.9.7.11266. Epub 2010 Apr 1. Cancer Biol Ther. 2010. PMID: 20150760 Free article.

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