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Page 1
Total synthesis of rapamycin.
Maddess ML, Tackett MN, Watanabe H, Brennan PE, Spilling CD, Scott JS, Osborn DP, Ley SV. Maddess ML, et al. Among authors: scott js. Angew Chem Int Ed Engl. 2007;46(4):591-7. doi: 10.1002/anie.200604053. Angew Chem Int Ed Engl. 2007. PMID: 17154218 No abstract available.
Total synthesis of rapamycin.
Ley SV, Tackett MN, Maddess ML, Anderson JC, Brennan PE, Cappi MW, Heer JP, Helgen C, Kori M, Kouklovsky C, Marsden SP, Norman J, Osborn DP, Palomero MA, Pavey JB, Pinel C, Robinson LA, Schnaubelt J, Scott JS, Spilling CD, Watanabe H, Wesson KE, Willis MC. Ley SV, et al. Among authors: scott js. Chemistry. 2009;15(12):2874-914. doi: 10.1002/chem.200801656. Chemistry. 2009. PMID: 19204960
The synthesis of azadirachtin: a potent insect antifeedant.
Ley SV, Abad-Somovilla A, Anderson JC, Ayats C, Bänteli R, Beckmann E, Boyer A, Brasca MG, Brice A, Broughton HB, Burke BJ, Cleator E, Craig D, Denholm AA, Denton RM, Durand-Reville T, Gobbi LB, Göbel M, Gray BL, Grossmann RB, Gutteridge CE, Hahn N, Harding SL, Jennens DC, Jennens L, Lovell PJ, Lovell HJ, de la Puente ML, Kolb HC, Koot WJ, Maslen SL, McCusker CF, Mattes A, Pape AR, Pinto A, Santafianos D, Scott JS, Smith SC, Somers AQ, Spilling CD, Stelzer F, Toogood PL, Turner RM, Veitch GE, Wood A, Zumbrunn C. Ley SV, et al. Among authors: scott js. Chemistry. 2008;14(34):10683-704. doi: 10.1002/chem.200801103. Chemistry. 2008. PMID: 18821532
Emerging roles of cohesin-STAG2 in cancer.
Scott JS, Al Ayadi L, Epeslidou E, van Scheppingen RH, Mukha A, Kaaij LJT, Lutz C, Prekovic S. Scott JS, et al. Oncogene. 2024 Nov 29. doi: 10.1038/s41388-024-03221-y. Online ahead of print. Oncogene. 2024. PMID: 39613934 Review.
Property-based optimisation of PROTACs.
Scott JS, Michaelides IN, Schade M. Scott JS, et al. RSC Med Chem. 2024 Nov 7. doi: 10.1039/d4md00769g. Online ahead of print. RSC Med Chem. 2024. PMID: 39553465 Free PMC article.
Discovery and In Vivo Efficacy of AZ-PRMT5i-1, a Novel PRMT5 Inhibitor with High MTA Cooperativity.
Smith JM, Barlaam B, Beattie D, Bradshaw L, Chan HM, Chiarparin E, Collingwood O, Cooke SL, Cronin A, Cumming I, Dean E, Debreczeni JÉ, Del Barco Barrantes I, Diene C, Gianni D, Guerot C, Guo X, Guven S, Hayhow TG, Hong T, Kemmitt PD, Lamont GM, Lamont S, Lynch JT, McWilliams L, Moore S, Raubo P, Robb GR, Robinson J, Scott JS, Srinivasan B, Steward O, Stubbs CJ, Syson K, Tan L, Turner O, Underwood E, Urosevic J, Vazquez-Chantada M, Whittaker AL, Wilson DM, Winter-Holt JJ. Smith JM, et al. Among authors: scott js. J Med Chem. 2024 Aug 22;67(16):13604-13638. doi: 10.1021/acs.jmedchem.4c00097. Epub 2024 Jul 30. J Med Chem. 2024. PMID: 39080842
Structural and Physicochemical Features of Oral PROTACs.
Schade M, Scott JS, Hayhow TG, Pike A, Terstiege I, Ahlqvist M, Johansson JR, Diene CR, Fallan C, Balazs AYS, Chiarparin E, Wilson D. Schade M, et al. Among authors: scott js. J Med Chem. 2024 Aug 8;67(15):13106-13116. doi: 10.1021/acs.jmedchem.4c01017. Epub 2024 Jul 30. J Med Chem. 2024. PMID: 39078401
Discovery of a Series of Orally Bioavailable Androgen Receptor Degraders for the Treatment of Prostate Cancer.
Bagal SK, Astles PC, Diène C, Argyrou A, Crafter C, Cassar DJ, Fallan C, Hock A, Jones T, Moreau K, Lamont GM, Lamont S, Michaloglou C, Packer MJ, Pike A, Ramos-Montoya A, Scott JS, Shaw J, Shologu Z. Bagal SK, et al. Among authors: scott js. J Med Chem. 2024 Jul 25;67(14):11732-11750. doi: 10.1021/acs.jmedchem.4c00269. Epub 2024 Jul 11. J Med Chem. 2024. PMID: 38991141
410 results