Sinclair DA - Search Results

1

Design and synthesis of compounds that extend yeast replicative lifespan.

Yang H, Baur JA, Chen A, Miller C, Adams JK, Kisielewski A, Howitz KT, Zipkin RE, Sinclair DA. Yang H, et al. Among authors: sinclair da. Aging Cell. 2007 Feb;6(1):35-43. doi: 10.1111/j.1474-9726.2006.00259.x. Epub 2006 Dec 5. Aging Cell. 2007. PMID: 17156081 Free PMC article.

2

Paradigms and pitfalls of yeast longevity research.

Sinclair DA. Sinclair DA. Mech Ageing Dev. 2002 Apr 30;123(8):857-67. doi: 10.1016/s0047-6374(02)00023-4. Mech Ageing Dev. 2002. PMID: 12044934 Review.

3

Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1.

Bitterman KJ, Anderson RM, Cohen HY, Latorre-Esteves M, Sinclair DA. Bitterman KJ, et al. Among authors: sinclair da. J Biol Chem. 2002 Nov 22;277(47):45099-107. doi: 10.1074/jbc.M205670200. Epub 2002 Sep 23. J Biol Chem. 2002. PMID: 12297502 Free article.

4

Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae.

Anderson RM, Bitterman KJ, Wood JG, Medvedik O, Sinclair DA. Anderson RM, et al. Among authors: sinclair da. Nature. 2003 May 8;423(6936):181-5. doi: 10.1038/nature01578. Nature. 2003. PMID: 12736687 Free PMC article.

5

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan.

Howitz KT, Bitterman KJ, Cohen HY, Lamming DW, Lavu S, Wood JG, Zipkin RE, Chung P, Kisielewski A, Zhang LL, Scherer B, Sinclair DA. Howitz KT, et al. Among authors: sinclair da. Nature. 2003 Sep 11;425(6954):191-6. doi: 10.1038/nature01960. Epub 2003 Aug 24. Nature. 2003. PMID: 12939617

6

Yeast life-span extension by calorie restriction is independent of NAD fluctuation.

Anderson RM, Latorre-Esteves M, Neves AR, Lavu S, Medvedik O, Taylor C, Howitz KT, Santos H, Sinclair DA. Anderson RM, et al. Among authors: sinclair da. Science. 2003 Dec 19;302(5653):2124-2126. doi: 10.1126/science.1088697. Epub 2003 Nov 6. Science. 2003. PMID: 14605207 Free PMC article.

7

Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis.

Cohen HY, Lavu S, Bitterman KJ, Hekking B, Imahiyerobo TA, Miller C, Frye R, Ploegh H, Kessler BM, Sinclair DA. Cohen HY, et al. Among authors: sinclair da. Mol Cell. 2004 Mar 12;13(5):627-38. doi: 10.1016/s1097-2765(04)00094-2. Mol Cell. 2004. PMID: 15023334 Free article.

8

Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase.

Cohen HY, Miller C, Bitterman KJ, Wall NR, Hekking B, Kessler B, Howitz KT, Gorospe M, de Cabo R, Sinclair DA. Cohen HY, et al. Among authors: sinclair da. Science. 2004 Jul 16;305(5682):390-2. doi: 10.1126/science.1099196. Epub 2004 Jun 17. Science. 2004. PMID: 15205477

9

Sirtuin activators mimic caloric restriction and delay ageing in metazoans.

Wood JG, Rogina B, Lavu S, Howitz K, Helfand SL, Tatar M, Sinclair D. Wood JG, et al. Nature. 2004 Aug 5;430(7000):686-9. doi: 10.1038/nature02789. Epub 2004 Jul 14. Nature. 2004. PMID: 15254550

10

Small molecules that regulate lifespan: evidence for xenohormesis.

Lamming DW, Wood JG, Sinclair DA. Lamming DW, et al. Among authors: sinclair da. Mol Microbiol. 2004 Aug;53(4):1003-9. doi: 10.1111/j.1365-2958.2004.04209.x. Mol Microbiol. 2004. PMID: 15306006 Free article. Review.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

282 results

Search Page

Filters