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Experimental validation of miRNA targets.
Kuhn DE, Martin MM, Feldman DS, Terry AV Jr, Nuovo GJ, Elton TS. Kuhn DE, et al. Methods. 2008 Jan;44(1):47-54. doi: 10.1016/j.ymeth.2007.09.005. Methods. 2008. PMID: 18158132 Free PMC article. Review.
Human chromosome 21-derived miRNAs are overexpressed in down syndrome brains and hearts.
Kuhn DE, Nuovo GJ, Martin MM, Malana GE, Pleister AP, Jiang J, Schmittgen TD, Terry AV Jr, Gardiner K, Head E, Feldman DS, Elton TS. Kuhn DE, et al. Biochem Biophys Res Commun. 2008 Jun 6;370(3):473-7. doi: 10.1016/j.bbrc.2008.03.120. Epub 2008 Apr 1. Biochem Biophys Res Commun. 2008. Retraction in: Biochem Biophys Res Commun. 2013 Jul 5;436(3):564. doi: 10.1016/j.bbrc.2013.06.083 PMID: 18387358 Free PMC article. Retracted.
miR-1 overexpression enhances Ca(2+) release and promotes cardiac arrhythmogenesis by targeting PP2A regulatory subunit B56alpha and causing CaMKII-dependent hyperphosphorylation of RyR2.
Terentyev D, Belevych AE, Terentyeva R, Martin MM, Malana GE, Kuhn DE, Abdellatif M, Feldman DS, Elton TS, Györke S. Terentyev D, et al. Among authors: kuhn de. Circ Res. 2009 Feb 27;104(4):514-21. doi: 10.1161/CIRCRESAHA.108.181651. Epub 2009 Jan 8. Circ Res. 2009. PMID: 19131648 Free PMC article.
Chromosome 21-derived microRNAs provide an etiological basis for aberrant protein expression in human Down syndrome brains.
Kuhn DE, Nuovo GJ, Terry AV Jr, Martin MM, Malana GE, Sansom SE, Pleister AP, Beck WD, Head E, Feldman DS, Elton TS. Kuhn DE, et al. J Biol Chem. 2010 Jan 8;285(2):1529-43. doi: 10.1074/jbc.M109.033407. Epub 2009 Nov 6. J Biol Chem. 2010. Retraction in: J Biol Chem. 2013 Feb 8;288(6):4228. doi: 10.1074/jbc.A109.033407 PMID: 19897480 Free PMC article. Retracted.
47 results