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Maturation of monocyte-derived dendritic cells with Toll-like receptor 3 and 7/8 ligands combined with prostaglandin E2 results in high interleukin-12 production and cell migration.
Boullart AC, Aarntzen EH, Verdijk P, Jacobs JF, Schuurhuis DH, Benitez-Ribas D, Schreibelt G, van de Rakt MW, Scharenborg NM, de Boer A, Kramer M, Figdor CG, Punt CJ, Adema GJ, de Vries IJ. Boullart AC, et al. Among authors: verdijk p. Cancer Immunol Immunother. 2008 Nov;57(11):1589-97. doi: 10.1007/s00262-008-0489-2. Epub 2008 Mar 6. Cancer Immunol Immunother. 2008. PMID: 18322684 Free PMC article.
Limited amounts of dendritic cells migrate into the T-cell area of lymph nodes but have high immune activating potential in melanoma patients.
Verdijk P, Aarntzen EH, Lesterhuis WJ, Boullart AC, Kok E, van Rossum MM, Strijk S, Eijckeler F, Bonenkamp JJ, Jacobs JF, Blokx W, Vankrieken JH, Joosten I, Boerman OC, Oyen WJ, Adema G, Punt CJ, Figdor CG, de Vries IJ. Verdijk P, et al. Clin Cancer Res. 2009 Apr 1;15(7):2531-40. doi: 10.1158/1078-0432.CCR-08-2729. Epub 2009 Mar 24. Clin Cancer Res. 2009. PMID: 19318472 Free article.
In situ expression of tumor antigens by messenger RNA-electroporated dendritic cells in lymph nodes of melanoma patients.
Schuurhuis DH, Verdijk P, Schreibelt G, Aarntzen EH, Scharenborg N, de Boer A, van de Rakt MW, Kerkhoff M, Gerritsen MJ, Eijckeler F, Bonenkamp JJ, Blokx W, van Krieken JH, Boerman OC, Oyen WJ, Punt CJ, Figdor CG, Adema GJ, de Vries IJ. Schuurhuis DH, et al. Among authors: verdijk p. Cancer Res. 2009 Apr 1;69(7):2927-34. doi: 10.1158/0008-5472.CAN-08-3920. Epub 2009 Mar 24. Cancer Res. 2009. PMID: 19318559
Targeting of 111In-labeled dendritic cell human vaccines improved by reducing number of cells.
Aarntzen EH, Srinivas M, Bonetto F, Cruz LJ, Verdijk P, Schreibelt G, van de Rakt M, Lesterhuis WJ, van Riel M, Punt CJ, Adema GJ, Heerschap A, Figdor CG, Oyen WJ, de Vries IJ. Aarntzen EH, et al. Among authors: verdijk p. Clin Cancer Res. 2013 Mar 15;19(6):1525-33. doi: 10.1158/1078-0432.CCR-12-1879. Epub 2013 Feb 4. Clin Cancer Res. 2013. PMID: 23382117 Free article. Clinical Trial.
Efficient identification of novel HLA-A(*)0201-presented cytotoxic T lymphocyte epitopes in the widely expressed tumor antigen PRAME by proteasome-mediated digestion analysis.
Kessler JH, Beekman NJ, Bres-Vloemans SA, Verdijk P, van Veelen PA, Kloosterman-Joosten AM, Vissers DC, ten Bosch GJ, Kester MG, Sijts A, Wouter Drijfhout J, Ossendorp F, Offringa R, Melief CJ. Kessler JH, et al. Among authors: verdijk p. J Exp Med. 2001 Jan 1;193(1):73-88. doi: 10.1084/jem.193.1.73. J Exp Med. 2001. PMID: 11136822 Free PMC article.
31 results