Majo VJ - Search Results

1

Synthesis and in vivo evaluation of [18F]-4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide as a PET imaging probe for COX-2 expression.

Prabhakaran J, Underwood MD, Parsey RV, Arango V, Majo VJ, Simpson NR, Van Heertum R, Mann JJ, Kumar JS. Prabhakaran J, et al. Among authors: majo vj. Bioorg Med Chem. 2007 Feb 15;15(4):1802-7. doi: 10.1016/j.bmc.2006.11.033. Epub 2006 Nov 29. Bioorg Med Chem. 2007. PMID: 17166726

2

Synthesis of [O-methyl-11C]1-(2-chlorophenyl)-5-(4-methoxyphenyl)-4-methyl-1H-pyrazole-3-carboxylic acid piperidin-1-ylamide: a potential PET ligand for CB1 receptors.

Kumar JS, Prabhakaran J, Arango V, Parsey RV, Underwood MD, Simpson NR, Kassir SA, Majo VJ, Van Heertum RL, Mann JJ. Kumar JS, et al. Among authors: majo vj. Bioorg Med Chem Lett. 2004 May 17;14(10):2393-6. doi: 10.1016/j.bmcl.2004.03.034. Bioorg Med Chem Lett. 2004. PMID: 15109619

3

A general method for the synthesis of aryl [11C]methylsulfones: potential PET probes for imaging cyclooxygenase-2 expression.

Majo VJ, Prabhakaran J, Simpson NR, Van Heertum RL, Mann JJ, Kumar JS. Majo VJ, et al. Bioorg Med Chem Lett. 2005 Oct 1;15(19):4268-71. doi: 10.1016/j.bmcl.2005.06.080. Bioorg Med Chem Lett. 2005. PMID: 16054359

4

Synthesis and in vivo validation of [O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)piperazin- 1-yl]butyl}-4-methyl-2H-[1,2,4]triazine-3,5-dione: a novel 5-HT1A receptor agonist positron emission tomography ligand.

Kumar JS, Majo VJ, Hsiung SC, Millak MS, Liu KP, Tamir H, Prabhakaran J, Simpson NR, Van Heertum RL, Mann JJ, Parsey RV. Kumar JS, et al. Among authors: majo vj. J Med Chem. 2006 Jan 12;49(1):125-34. doi: 10.1021/jm050725j. J Med Chem. 2006. PMID: 16392798

5

Synthesis, in vitro and in vivo evaluation of [O-methyl-11C] 2-{4-[4-(3-methoxyphenyl)piperazin-1-yl]-butyl}-4-methyl-2H-[1,2,4]-triazine-3,5-dione: a novel agonist 5-HT1A receptor PET ligand.

Prabhakaran J, Parsey RV, Majo VJ, Hsiung SC, Milak MS, Tamir H, Simpson NR, Van Heertum RL, Mann JJ, Dileep Kumar JS. Prabhakaran J, et al. Among authors: majo vj. Bioorg Med Chem Lett. 2006 Apr 15;16(8):2101-4. doi: 10.1016/j.bmcl.2006.01.052. Epub 2006 Feb 3. Bioorg Med Chem Lett. 2006. PMID: 16458504

6

Synthesis and in vivo evaluation of [11C]SN003 as a PET ligand for CRF1 receptors.

Kumar JS, Majo VJ, Sullivan GM, Prabhakaran J, Simpson NR, Van Heertum RL, Mann JJ, Parsey RV. Kumar JS, et al. Among authors: majo vj. Bioorg Med Chem. 2006 Jun 15;14(12):4029-34. doi: 10.1016/j.bmc.2006.02.019. Epub 2006 Mar 10. Bioorg Med Chem. 2006. PMID: 16529935

7

Synthesis and in vivo evaluation of [O-methyl-11C](2R,4R)-4-hydroxy-2-[2-[2-[2-(3-methoxy)phenyl]ethyl]phenoxy]ethyl-1-methylpyrrolidine as a 5-HT2A receptor PET ligand.

Kumar JS, Prabhakaran J, Erlandsson K, Majo VJ, Simpson NR, Pratap M, Van Heertum RL, Mann JJ, Parsey RV. Kumar JS, et al. Among authors: majo vj. Nucl Med Biol. 2006 May;33(4):565-74. doi: 10.1016/j.nucmedbio.2006.02.001. Epub 2006 May 2. Nucl Med Biol. 2006. PMID: 16720250

8

In vitro and in vivo evaluation of [11C]MPEPy as a potential PET ligand for mGlu5 receptors.

Severance AJ, Parsey RV, Kumar JS, Underwood MD, Arango V, Majo VJ, Prabhakaran J, Simpson NR, Van Heertum RL, Mann JJ. Severance AJ, et al. Among authors: majo vj. Nucl Med Biol. 2006 Nov;33(8):1021-7. doi: 10.1016/j.nucmedbio.2006.09.007. Nucl Med Biol. 2006. PMID: 17127176

9

In vivo assessment of [11C]MRB as a prospective PET ligand for imaging the norepinephrine transporter.

Severance AJ, Milak MS, Kumar JSD, Prabhakaran J, Majo VJ, Simpson NR, Van Heertum RL, Arango V, Mann JJ, Parsey RV. Severance AJ, et al. Among authors: majo vj. Eur J Nucl Med Mol Imaging. 2007 May;34(5):688-693. doi: 10.1007/s00259-006-0312-2. Epub 2006 Dec 19. Eur J Nucl Med Mol Imaging. 2007. PMID: 17180600

10

Synthesis and in vivo evaluation of a novel 5-HT1A receptor agonist radioligand [O-methyl- 11C]2-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-4-methyl-1,2,4-triazine-3,5(2H,4H)dione in nonhuman primates.

Kumar JS, Prabhakaran J, Majo VJ, Milak MS, Hsiung SC, Tamir H, Simpson NR, Van Heertum RL, Mann JJ, Parsey RV. Kumar JS, et al. Among authors: majo vj. Eur J Nucl Med Mol Imaging. 2007 Jul;34(7):1050-60. doi: 10.1007/s00259-006-0324-y. Epub 2007 Jan 13. Eur J Nucl Med Mol Imaging. 2007. PMID: 17221184

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