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Intestinal expression of P-glycoprotein (ABCB1), multidrug resistance associated protein 2 (ABCC2), and uridine diphosphate-glucuronosyltransferase 1A1 predicts the disposition and modulates the effects of the cholesterol absorption inhibitor ezetimibe in humans.
Oswald S, Haenisch S, Fricke C, Sudhop T, Remmler C, Giessmann T, Jedlitschky G, Adam U, Dazert E, Warzok R, Wacke W, Cascorbi I, Kroemer HK, Weitschies W, von Bergmann K, Siegmund W. Oswald S, et al. Among authors: jedlitschky g. Clin Pharmacol Ther. 2006 Mar;79(3):206-17. doi: 10.1016/j.clpt.2005.11.004. Epub 2006 Feb 7. Clin Pharmacol Ther. 2006. PMID: 16513445
Modification of OATP2B1-mediated transport by steroid hormones.
Grube M, Köck K, Karner S, Reuther S, Ritter CA, Jedlitschky G, Kroemer HK. Grube M, et al. Among authors: jedlitschky g. Mol Pharmacol. 2006 Nov;70(5):1735-41. doi: 10.1124/mol.106.026450. Epub 2006 Aug 14. Mol Pharmacol. 2006. PMID: 16908597
Human platelets express organic anion-transporting peptide 2B1, an uptake transporter for atorvastatin.
Niessen J, Jedlitschky G, Grube M, Bien S, Schwertz H, Ohtsuki S, Kawakami H, Kamiie J, Oswald S, Starke K, Strobel U, Siegmund W, Rosskopf D, Greinacher A, Terasaki T, Kroemer HK. Niessen J, et al. Among authors: jedlitschky g. Drug Metab Dispos. 2009 May;37(5):1129-37. doi: 10.1124/dmd.108.024570. Epub 2009 Feb 23. Drug Metab Dispos. 2009. PMID: 19237515
Expression and localization of the multidrug resistance protein 5 (MRP5/ABCC5), a cellular export pump for cyclic nucleotides, in human heart.
Dazert P, Meissner K, Vogelgesang S, Heydrich B, Eckel L, Böhm M, Warzok R, Kerb R, Brinkmann U, Schaeffeler E, Schwab M, Cascorbi I, Jedlitschky G, Kroemer HK. Dazert P, et al. Among authors: jedlitschky g. Am J Pathol. 2003 Oct;163(4):1567-77. doi: 10.1016/S0002-9440(10)63513-4. Am J Pathol. 2003. PMID: 14507663 Free PMC article.
95 results